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Articles Published Processes
3/28/2016 3:05:00 PM | Browse: 1096 | Download: 1609
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Received |
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2015-12-22 09:15 |
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Peer-Review Started |
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2015-12-22 15:34 |
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To Make the First Decision |
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2016-01-28 14:37 |
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Return for Revision |
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2016-01-28 15:56 |
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Revised |
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2016-02-12 02:05 |
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Second Decision |
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2016-02-19 09:22 |
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Accepted by Journal Editor-in-Chief |
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2016-02-19 15:47 |
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Accepted by Executive Editor-in-Chief |
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2016-03-02 08:16 |
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Articles in Press |
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2016-03-02 08:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-03-14 10:11 |
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Publish the Manuscript Online |
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2016-03-28 15:05 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Liver cancer stem cell markers: Progression and therapeutic implications
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jing-Hui Sun, Qing Luo, Ling-Ling Liu and Guan-Bin Song |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
11272365 |
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| Corresponding Author |
Guan-bin Song, PhD, Professor of Biomedical Engineering, Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, No.174, Shapingba Street, Shapingba District, Chongqing 400044,
China. song@cqu.edu.cn
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| Key Words |
Liver cancer; Cancer recurrence; Liver cancer stem cells; Cancer stem cell markers; Targeted therapy |
| Core Tip |
Liver cancer is the fifth most common cancer and the third leading cause of cancer-related mortality worldwide despite remarkable progress in understanding hepatocarcinogenesis and new therapeutic approaches. Recently, the presence of highly resistant cancer stem cells (CSCs) in liver cancer has been proposed to be responsible for tumor growth, invasion, metastasis and recurrence. CSC involvement in liver cancer pathogenesis also highlights them as preferential targets for therapy. This review specifically focuses on the markers used to define human liver cancer stem cells, the therapeutic implications of the expression of these markers in patient’s primary tumors, and the potential of the markers to serve as therapeutic targets.
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| Publish Date |
2016-03-28 15:05 |
| Citation |
Sun JH, Luo Q, Liu LL, Song GB. Liver cancer stem cell markers: Progression and therapeutic implications. World J Gastroenterol 2016; 22(13): 3547-3557 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i13/3547.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i13.3547 |
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