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5/13/2016 2:24:00 PM | Browse: 655 | Download: 983
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 24003
Country/Territory United States
2015-12-30 08:20
Peer-Review Started
2016-01-02 13:36
To Make the First Decision
2016-02-02 08:46
Return for Revision
2016-02-02 09:38
2016-03-01 04:41
Second Decision
2016-03-07 15:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-03-18 15:59
Articles in Press
2016-03-18 15:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-04-22 16:30
Publish the Manuscript Online
2016-05-12 16:59
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Sieving characteristics of cytokine- and peroxide-induced epithelial barrier leak: Inhibition by berberine
Manuscript Source Invited Manuscript
All Author List Katherine M DiGuilio, Christina M Mercogliano, Jillian Born, Brendan Ferraro, Julie To, Brittany Mixson, Allison Smith, Mary Carmen Valenzano and James M Mullin
Funding Agency and Grant Number
Corresponding author James M Mullin, PhD, AGAF, Professor, Lankenau Institute for Medical Research, Lankenau Medical Center, 100 Lancaster Avenue, Wynnewood, PA 19096, United States. mullinj@mlhs.org
Key Words Intestine; Crohn’s disease; Tight junction; Ulcerative colitis; CACO-2; Berberine; Micronutrient; Cytokine
Core Tip A cell culture model of graded transepithelial leak can be very valuable in evaluating the various types and magnitudes of leak that can exhibit across the inflammatory bowel disease mucosa. This graded leak can be achieved through various combinations of proinflammatory cytokines and peroxide. Berberine provides an example of a micronutrient that can be more effective against one type of induced leak than another.
Publish Date 2016-05-12 16:59
Citation DiGuilio KM, Mercogliano CM, Born J, Ferraro B, To J, Mixson B, Smith A, Valenzano MC, Mullin JM. Sieving characteristics of cytokine- and peroxide-induced epithelial barrier leak: Inhibition by berberine. World J Gastrointest Pathophysiol 2016; 7(2): 223-234
Url http://www.wjgnet.com/2150-5330/full/v7/i2/223.htm
DOI http://dx.doi.org/10.4291/wjgp.v7.i2.223
Full Article (PDF) WJGP-7-223.pdf
Full Article (Word) WJGP-7-223.doc
Manuscript File 24003-Review.docx
Answering Reviewers 24003-Answering reviewers.pdf
Audio Core Tip 24003-Audio core tip.mp3
Biostatistics Review Certificate 24003-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24003-Conflict-of-interest statement.pdf
Copyright License Agreement 24003-Copyright assignment.pdf
Data Sharing Statement 24003-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20151230003201.docx
Institutional Animal Care and Use Committee Approval Form or Document 24003-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 24003-Institutional review board statement.pdf
Supplementary Material Supplementary_Material_20151230003219.docx
Peer-review Report 24003-Peer-review(s).pdf
Scientific Misconduct Check 24003-Scientific misconduct check.pdf
Scientific Editor Work List 24003-Scientific editor work list.pdf