Publication Name	World Journal of Gastroenterology
Manuscript ID	24086
Country	Türkiye

Received	2016-01-06 08:51
Peer-Review Started	2016-01-06 16:25
To Make the First Decision	2016-01-28 14:46
Return for Revision	2016-01-28 15:16
Revised	2016-02-02 03:36
Second Decision	2016-02-22 13:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-03-02 09:27
Articles in Press	2016-03-02 09:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-03-22 06:54
Typeset the Manuscript	2016-04-07 09:08
Publish the Manuscript Online	2016-04-19 09:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Nonalcoholic fatty liver disease as a multi-systemic disease
Manuscript Source	Invited Manuscript
All Author List	Hakan Fotbolcu and Elçin Zorlu
Funding Agency and Grant Number
Corresponding Author	Hakan Fotbolcu, MD, Department of Cardiology, Pendik BölgeHastanesi, Emek Caddesi, No. 281, Narcity Konutları, A 2b Blok, Kat 9 D 56, Maltepe, Istanbul 34000, Turkey. hakan_fotbolcu@yahoo.com
Key Words	Nonalcoholic fatty liver disease; Obesity; Insulin resistance; Cardiovascular effect; Multi-systemic disease
Core Tip	Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked with insulin resistance. NAFLD should be considered not only a liver specific disease but also an early mediator of systemic diseases. Therefore, NAFLD is usually associated with cardiovascular disease, chronic kidney disease, type 2 diabetes, obesity, and dyslipidemia. This review focuses on the pathogenesis of NAFLD and its relation with other systemic diseases.
Publish Date	2016-04-19 09:42
Citation	Fotbolcu H, Zorlu E. Nonalcoholic fatty liver disease as a multi-systemic disease. World J Gastroenterol 2016; 22(16): 4079-4090
URL	http://www.wjgnet.com/1007-9327/full/v22/i16/4079.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i16.4079

Full Article (PDF)	WJG-22-4079.pdf
Full Article (Word)	WJG-22-4079.doc
Manuscript File	24086-Review.docx
Answering Reviewers	24086-Answering reviewers.pdf
Audio Core Tip	24086-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	24086-Conflict-of-interest statement.pdf
Copyright License Agreement	24086-Copyright assignment.pdf
Peer-review Report	24086-Peer-review(s).pdf
Scientific Misconduct Check	24086-Scientific misconduct check.pdf
Scientific Editor Work List	24086-Scientific editor work list.pdf