Publication Name	World Journal of Hepatology
Manuscript ID	24149
Country	United States

Received	2016-01-10 16:36
Peer-Review Started	2016-01-10 18:39
To Make the First Decision	2016-02-22 10:22
Return for Revision	2016-02-22 14:26
Revised	2016-03-08 07:31
Second Decision	2016-03-22 16:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-04-06 13:50
Articles in Press	2016-04-06 13:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-14 11:38
Publish the Manuscript Online	2016-04-19 14:32

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Topic Highlights
Article Title	Incidence, risk factors and outcomes of de novo malignancies post liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Pavan Kedar Mukthinuthalapati, Raghavender Gotur and Marwan Ghabril
Funding Agency and Grant Number
Corresponding Author	Marwan Ghabril, MD, Associate Pro­fessor of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, 702 Rotary Circle 225, Indianapolis, IN 46202, United States. mghabril@iu.edu
Key Words	Liver transplant; Immunosuppression; Risk; Outcomes; Malignancy
Core Tip	The risk of new cancers is significantly in-creased after liver transplantation (LT), and is driven by patient factors, oncogenic viruses and lifelong immunosuppression. De novo malignancy is a major risk factor for mortality after LT, equaling the risk of cardiovascular disease or infectious diseases. The risk of de novo malignancies may be reduced by attention to patient risk factors and minimization of immunosuppre-ssion when possible. Ultimately rigorous surveillance is needed to allow for early diagnosis and attenuation of mortality risk.
Publish Date	2016-04-19 14:32
Citation	Mukthinuthalapati PK, Gotur R, Ghabril M. Incidence, risk factors and outcomes of de novo malignancies post liver trans­plantation. World J Hepatol 2016; 8(12): 533-544
URL	http://www.wjgnet.com/1948-5182/full/v8/i12/533.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i12.533

Full Article (PDF)	WJH-8-533.pdf
Full Article (Word)	WJH-8-533.doc
Manuscript File	24149-Review.docx
Answering Reviewers	24149-Answering reviewers.pdf
Audio Core Tip	24149-Audio core tip.wav
Conflict-of-Interest Disclosure Form	24149-Conflict-of-interest statement.pdf
Copyright License Agreement	24149-Copyright assignment.pdf
Peer-review Report	24149-Peer-review(s).pdf
Scientific Misconduct Check	24149-Scientific misconduct check.pdf
Scientific Editor Work List	24149-Scientific editor work list.pdf