Publication Name	World Journal of Gastroenterology
Manuscript ID	24343
Country	Brazil

Received	2016-01-19 08:41
Peer-Review Started	2016-01-19 16:50
To Make the First Decision	2016-02-18 11:48
Return for Revision	2016-02-19 11:40
Revised	2016-03-01 06:31
Second Decision	2016-03-04 18:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-03-14 10:23
Articles in Press	2016-03-14 10:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-04-25 06:44
Typeset the Manuscript	2016-05-23 11:32
Publish the Manuscript Online	2016-06-02 15:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Pathology
Manuscript Type	Basic Study
Article Title	Apoptosis induced by a low-carbohydrate and high-protein diet in rat livers
Manuscript Source	Unsolicited Manuscript
All Author List	Maria Emília L Monteiro, Analucia R Xavier, Felipe L Oliveira, Porphirio JS Filho and Vilma B Azeredo
Funding Agency and Grant Number
Corresponding Author	Maria Emília L Monteiro, MD, MSc, professor, Department of Internal Medicine, Medicine College, Fluminense Federal University, Rua Mario Sardinha, 46, São Francisco, Niterói, RJ 24360-007, Brasil. lhcastroguedes@terra.com.br
Key Words	Apoptosis; Liver injury; High-protein diet; High-fat diet; Low-carbohydrate diet
Core Tip	Obesity is a serious and growing health problem. A high-protein, high-fat, and low-carbohydrate diet known as the Atkins diet has been adopted since the 1970s. Many people adhere to this diet in an attempt to lose weight, and it has recently been introduced for children with difficult-to-control seizures and elderly suffering from Alzheimer’s and Parkinson’s diseases. The benefits and effects of the Atkins diet remain unclear, especially in hepatic metabolism. Since the primary metabolic reactions involving macronutrients occur in the liver, it is essential to understand the potential hepatic lesions that can result from dietary modifications.
Publish Date	2016-06-02 15:26
Citation	Monteiro MEL, Xavier AR, Oliveira FL, Filho PJS, Azeredo VB. Apoptosis induced by a low-carbohydrate and high-protein diet in rat livers. World J Gastroenterol 2016; 22(22): 5165-5172
URL	http://www.wjgnet.com/1007-9327/full/v22/i22/5165.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i22.5165

Full Article (PDF)	WJG-22-5165.pdf
Full Article (Word)	WJG-22-5165.doc
Manuscript File	24343-Review.docx
Answering Reviewers	24343-Answering reviewers.pdf
Audio Core Tip	24343-Audio core tip.mp3
Biostatistics Review Certificate	24343-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	24343-Conflict-of-interest statement.pdf
Copyright License Agreement	24343-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	24343-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	24343-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	24343-Language certificate.pdf
Peer-review Report	24343-Peer-review(s).pdf
Scientific Misconduct Check	24343-Scientific misconduct check.pdf
Scientific Editor Work List	24343-Scientific editor work list.pdf