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5/30/2016 5:39:00 PM | Browse: 632 | Download: 1274
Publication Name World Journal of Gastroenterology
Manuscript ID 24493
Country of Manuscript Source Iran
Received
2016-02-12 10:39
Peer-Review Started
2016-02-13 21:07
To Make the First Decision
2016-03-31 10:08
Return for Revision
2016-03-31 16:46
Revised
2016-04-08 02:02
Second Decision
2016-04-26 11:59
Accepted by Journal Editor-in-Chief
2016-04-26 15:50
Accepted by Company Editor-in-Chief
2016-05-04 17:42
Articles in Press
2016-05-04 17:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-05-11 11:31
Publish the Manuscript Online
2016-05-30 17:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment
Manuscript Source Invited Manuscript
All Author List Seyedeh Farnaz Ghasemi-Niri, Faheem Maqbool, Maryam Baeeri, Mahdi Gholami and Mohammad Abdollahi
Funding Agency and Grant Number
Funding Agency Grant Number
Tehran University of Medical Sciences 93-02-45-26666
Corresponding author Mohammad Abdollahi, PhD, Professor, Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Enghelab Avenue, Tehran 1417614411, Iran. mohammad@tums.ac.ir
Keywords Organophosphorus; Phosalone; Ellagic acid; Inflammation; Oxidative stress; Colon
Core Tip This research uses a rat model to evaluate the colon related side effects of phosalone which is a member of the organophosphorus family. After feeding different dosages of phosalone to the rats for one month, the colon tissue of the rats were studied using oxidative stress and pathology tests. Both tests show that the higher doses of phosalone elevate reactive oxygen species (ROS), tumor necrosis factor-a, interlukin-6b and nuclear factor-kB proteins which result in more inflammation. In our study, ellagic acid (EA) which is a strong antioxidant reduced phosalone-induced side effects. The oxidative stress and pathology results concluded that EA helps reducing inflammation and ROS.
Publish Date 2016-05-30 17:40
Citation Ghasemi-Niri SF, Maqbool F, Baeeri M, Gholami M, Abdollahi M. Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment. World J Gastroenterol 2016; 22(21): 4999-5011
Url http://www.wjgnet.com/1007-9327/full/v22/i21/4999.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i21.4999
Full Article (PDF) WJG-22-4999.pdf
Full Article (Word) WJG-22-4999.doc
Manuscript File 24493-Review.docx
Answering Reviewers 24493-Answering reviewers.pdf
Audio Core Tip 24493-Audio core tip.mp3
Biostatistics Review Certificate 24493-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24493-Conflict-of-interest statement.pdf
Copyright License Agreement 24493-Copyright assignment .pdf
Data Sharing Statement 24493-Data sharing statement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 24493-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 24493-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 24493-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 24493-Language certificate.pdf
Supplementary Material Supplementary_Material_20160211155242.txt
Peer-review Report 24493-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24493-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24493-Scientific misconduct check.pdf
Scientific Editor Work List 24493-Scientific editor work list.pdf