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Articles Published Processes
5/30/2016 5:39:00 PM | Browse: 1342 | Download: 3152
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Received |
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2016-02-12 10:39 |
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Peer-Review Started |
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2016-02-13 21:07 |
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To Make the First Decision |
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2016-03-31 10:08 |
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Return for Revision |
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2016-03-31 16:46 |
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Revised |
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2016-04-08 02:02 |
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Second Decision |
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2016-04-26 11:59 |
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Accepted by Journal Editor-in-Chief |
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2016-04-26 15:50 |
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Accepted by Executive Editor-in-Chief |
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2016-05-04 17:42 |
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Articles in Press |
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2016-05-04 17:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-05-11 11:31 |
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Publish the Manuscript Online |
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2016-05-30 17:40 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Seyedeh Farnaz Ghasemi-Niri, Faheem Maqbool, Maryam Baeeri, Mahdi Gholami and Mohammad Abdollahi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tehran University of Medical Sciences |
93-02-45-26666 |
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| Corresponding Author |
Mohammad Abdollahi, PhD, Professor, Faculty of Pharmacy, and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Enghelab Avenue, Tehran 1417614411, Iran. mohammad@tums.ac.ir |
| Key Words |
Organophosphorus; Phosalone; Ellagic acid; Inflammation; Oxidative stress; Colon |
| Core Tip |
This research uses a rat model to evaluate the colon related side effects of phosalone which is a member of the organophosphorus family. After feeding different dosages of phosalone to the rats for one month, the colon tissue of the rats were studied using oxidative stress and pathology tests. Both tests show that the higher doses of phosalone elevate reactive oxygen species (ROS), tumor necrosis factor-a, interlukin-6b and nuclear factor-kB proteins which result in more inflammation. In our study, ellagic acid (EA) which is a strong antioxidant reduced phosalone-induced side effects. The oxidative stress and pathology results concluded that EA helps reducing inflammation and ROS. |
| Publish Date |
2016-05-30 17:40 |
| Citation |
Ghasemi-Niri SF, Maqbool F, Baeeri M, Gholami M, Abdollahi M. Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment. World J Gastroenterol 2016; 22(21): 4999-5011 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i21/4999.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i21.4999 |
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