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6/2/2016 3:32:00 PM | Browse: 1115 | Download: 1740
Publication Name World Journal of Gastroenterology
Manuscript ID 24559
Country Taiwan
Received
2016-01-28 10:19
Peer-Review Started
2016-01-28 17:48
To Make the First Decision
2016-03-07 09:32
Return for Revision
2016-03-08 10:04
Revised
2016-03-24 11:49
Second Decision
2016-03-28 14:00
Accepted by Journal Editor-in-Chief
2016-03-30 22:26
Accepted by Company Editor-in-Chief
2016-04-07 15:58
Articles in Press
2016-04-07 15:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-05-05 18:05
Publish the Manuscript Online
2016-06-02 15:26
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Chia-Sheng Yen, Zhi-Ru Su, Yi-Ping Lee, I-Ting Liu and Chia-Jui Yen
Funding Agency and Grant Number
Funding Agency Grant Number
National Cheng Kung University Hospital Research Fund NCKUH-10103002
Corresponding Author Chia-Jui Yen, MD, PhD, Associate Professor, Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 70403, Taiwan. yencj@mail.ncku.edu.tw
Key Words miR-106b; Hepatitis B virus; Hepatocellular carcinoma; Tumor progression; Hepatitis B virus X protein
Core Tip The role of miR-106b in tumor progression of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) and how it be regulated are still unclear. In this study, we analyzed the expression levels of miR-106b in HBV-associated HCC tissues and correlated the data with clinical records of patients. Our results indicated that miR-106b expression was up-regulated and related with tumor progression in HBV-associated HCC. In addition, hepatitis B virus X protein may contribute to enhance the transcription of miR-106b. These findings provide potential diagnostic and therapeutic targets for HBV-associated HCC.
Publish Date 2016-06-02 15:26
Citation Yen CS, Su ZR, Lee YP, Liu IT, Yen CJ. miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma. World J Gastroenterol 2016; 22(22): 5183-5192
URL http://www.wjgnet.com/1007-9327/full/v22/i22/5183.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i22.5183
Full Article (PDF) WJG-22-5183.pdf
Full Article (Word) WJG-22-5183.doc
Manuscript File 24559-Review.docx
Answering Reviewers 24559-Answering reviewers.pdf
Audio Core Tip 24559-Audio core tip.mp3
Biostatistics Review Certificate 24559-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24559-Conflict-of-interest statement.pdf
Copyright License Agreement 24559-Copyright assignment.docx
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 24559-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 24559-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 24559-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 24559-Language certificate.pdf
Peer-review Report 24559-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24559-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24559-Scientific misconduct check.pdf
Scientific Editor Work List 24559-Scientific editor work list.pdf