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Articles Published Processes
6/2/2016 3:32:00 PM | Browse: 1248 | Download: 2185
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Received |
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2016-01-28 10:19 |
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Peer-Review Started |
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2016-01-28 17:48 |
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To Make the First Decision |
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2016-03-07 09:32 |
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Return for Revision |
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2016-03-08 10:04 |
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Revised |
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2016-03-24 11:49 |
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Second Decision |
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2016-03-28 14:00 |
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Accepted by Journal Editor-in-Chief |
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2016-03-30 22:26 |
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Accepted by Executive Editor-in-Chief |
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2016-04-07 15:58 |
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Articles in Press |
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2016-04-07 15:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-05-05 18:05 |
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Publish the Manuscript Online |
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2016-06-02 15:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chia-Sheng Yen, Zhi-Ru Su, Yi-Ping Lee, I-Ting Liu and Chia-Jui Yen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Cheng Kung University Hospital Research Fund |
NCKUH-10103002 |
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| Corresponding Author |
Chia-Jui Yen, MD, PhD, Associate Professor, Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan 70403, Taiwan. yencj@mail.ncku.edu.tw
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| Key Words |
miR-106b; Hepatitis B virus; Hepatocellular carcinoma; Tumor progression; Hepatitis B virus X protein |
| Core Tip |
The role of miR-106b in tumor progression of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) and how it be regulated are still unclear. In this study, we analyzed the expression levels of miR-106b in HBV-associated HCC tissues and correlated the data with clinical records of patients. Our results indicated that miR-106b expression was up-regulated and related with tumor progression in HBV-associated HCC. In addition, hepatitis B virus X protein may contribute to enhance the transcription of miR-106b. These findings provide potential diagnostic and therapeutic targets for HBV-associated HCC.
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| Publish Date |
2016-06-02 15:26 |
| Citation |
Yen CS, Su ZR, Lee YP, Liu IT, Yen CJ. miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma. World J Gastroenterol 2016; 22(22): 5183-5192 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i22/5183.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i22.5183 |
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