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Articles Published Processes
8/1/2016 9:43:00 AM | Browse: 842 | Download: 1498
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Received |
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2016-02-09 11:59 |
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Peer-Review Started |
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2016-02-14 13:21 |
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To Make the First Decision |
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2016-03-21 13:53 |
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Return for Revision |
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2016-03-21 17:51 |
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Revised |
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2016-04-20 09:03 |
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Second Decision |
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2016-05-05 17:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-05-27 10:39 |
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Articles in Press |
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2016-05-27 10:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-07-26 15:12 |
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Publish the Manuscript Online |
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2016-08-01 09:43 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Risk of second primary malignancies in a population-based study of adult patients with essential thrombocythemia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rajesh Shrestha, Smith Giri, Ranjan Pathak and Vijaya Raj Bhatt |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Nebraska Medical Center, College of Medicine, Physician-Scientist Training Program Grant 2015-2016 |
to Bhatt VR |
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| Corresponding Author |
Vijaya Raj Bhatt, MD, Division of Hematology and Oncology, Department of Internal Medicine, University of Nebraska Medical Center, 42nd and Emile, Nebraska, NE 68191, United States. vijaya.bhatt@unmc.edu |
| Key Words |
Essential thrombocythemia; Second primary malignancy; Survival |
| Core Tip |
Second primary malignancy (SPM) contributes to worse survival in essential thrombocythemia (ET). We utilized the Surveillance, Epidemiology and End Results database to analyze the risk of SPM in ET patients diagnosed during 2001-2011. Two hundred and one patients (2.46%) developed SPM at a median age of 75 years. SPMs occurred at an observed/expected (O/E) ratio of 1.26 (95%CI: 1.09-1.45, P = 0.002) with an absolute excess risk of 37.44 per 10000 population. A significantly higher risk was noted for leukemia (O/E 3.78; 95%CI: 2.20-6.05, P < 0.001). An increased risk of SPM, particularly leukemia, may contribute to excess deaths in ET. |
| Publish Date |
2016-08-01 09:43 |
| Citation |
Shrestha R, Giri S, Pathak R, Bhatt VR. Risk of second primary malignancies in a population-based study of adult patients with essential thrombocythemia. World J Clin Oncol 2016; 7(4): 324-330 |
| URL |
http://www.wjgnet.com/2218-4333/full/v7/i4/324.htm |
| DOI |
http://dx.doi.org/10.5306/wjco.v7.i4.324 |
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