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7/29/2016 8:32:00 PM | Browse: 512 | Download: 902
Publication Name World Journal of Gastroenterology
Manuscript ID 24816
Country/Territory United States
Received
2016-02-10 14:51
Peer-Review Started
2016-02-10 19:40
To Make the First Decision
2016-03-07 08:31
Return for Revision
2016-03-08 16:31
Revised
2016-03-28 18:53
Second Decision
2016-04-26 12:06
Accepted by Journal Editor-in-Chief
2016-04-28 23:00
Accepted by Company Editor-in-Chief
2016-05-23 16:47
Articles in Press
2016-05-23 16:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-07-21 10:33
Publish the Manuscript Online
2016-07-29 20:32
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Systematic Review
Article Title Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review
Manuscript Source Unsolicited Manuscript
All Author List Tyler J Severson, Siddesh Besur and Herbert L Bonkovsky
Funding Agency and Grant Number
Corresponding author Herbert L Bonkovsky, MD, Professor, Department of Gastroenterology and Hepatology, Wake Forest University NC Baptist Medical Center, Nutrition Bldg, E-112, 1 Medical Center Blvd, Winston-Salem, NC 27157, United States. hbonkovs@wakehealth.edu
Keywords Genetic polymorphisms; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; PNPLA3; TM6SF2; FTO; Cirrhosis; Iron metabolism
Core Tip Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions not only in the United States but worldwide. Its end results can include non-alcoholic steatohepatitis, cirrhosis, liver failure, and hepatocellular carcinoma. Studies since 2008 have demonstrated and continue to uncover noteworthy genetic factors that influence NAFLD and its onset, severity, and ultimate outcome. Awareness of these genetic elements yields improved understanding of the pathology of the disease and will likely be key to individualizing effective patient therapy in the near future.
Publish Date 2016-07-29 20:32
Citation Severson TJ, Besur S, Bonkovsky HL. Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review. World J Gastroenterol 2016; 22(29): 6742-6756
Url http://www.wjgnet.com/1007-9327/full/v22/i29/6742.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i29.6742
Full Article (PDF) WJG-22-6742.pdf
Full Article (Word) WJG-22-6742.doc
Manuscript File 24816-Review.docx
Answering Reviewers 24816-Answering reviewers.pdf
Audio Core Tip 24816-Audio core tip.wav
Biostatistics Review Certificate 24816-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 24816-Conflict-of-interest statement.pdf
Copyright License Agreement 24816-Copyright assignment.pdf
Data Sharing Statement 24816-Data sharing statement.pdf
Peer-review Report 24816-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 24816-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 24816-Scientific misconduct check.pdf
Scientific Editor Work List 24816-Scientific editor work list.pdf