ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Randomized Controlled Trial |
Article Title |
Randomized study of lafutidine vs lansoprazole in patients with mild gastroesophageal reflux disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Ryuta Takenaka, Hiroyuki Okada, Seiji Kawano, Yoshinori Komazawa, Fumiya Yoshinaga, Shinji Nagata, Masafumi Inoue, Hirohisa Komatsu, Seiji Onogawa, Yoshinori Kushiyama, Shinichi Mukai, Hiroko Todo, Hideharu Okanobu, Noriaki Manabe, Shinji Tanaka, Ken Haruma and Yoshikazu Kinoshita |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Taiho Pharmaceutical Co. Ltd |
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Corresponding Author |
Ryuta Takenaka, MD, PhD, Department of Gastroenterology, Tsuyama Chuo Hospital, 1756 Kawasaki, Tsuyama 708-0841, Japan. rtakenak@tch.or.jp
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Key Words |
Gastroesophageal reflux disease; Proton pump inhibitors; Histamine receptor-2 antagonists; Los Angeles classification |
Core Tip |
The clinical efficacy of the second-generation H2RA lafutidine was inferior to that of lansoprazole, particularly during maintenance therapy, even in Japanese patients with mild gastroesophageal reflux disease. |
Publish Date |
2016-06-13 09:14 |
Citation |
Takenaka R, Okada H, Kawano S, Komazawa Y, Yoshinaga F, Nagata S, Inoue M, Komatsu H, Onogawa S, Kushiyama Y, Mukai S, Todo H, Okanobu H, Manabe N, Tanaka S, Haruma K, Kinoshita Y. Randomized study of lafutidine vs lansoprazole in patients with mild gastroesophageal reflux disease. World J Gastroenterol 2016; 22(23): 5430-5435 |
URL |
http://www.wjgnet.com/1007-9327/full/v22/i23/5430.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v22.i23.5430 |