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Articles Published Processes
6/2/2016 3:32:00 PM | Browse: 1044 | Download: 2206
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Received |
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2016-02-18 09:23 |
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Peer-Review Started |
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2016-02-19 13:50 |
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To Make the First Decision |
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2016-03-31 09:51 |
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Return for Revision |
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2016-04-01 11:25 |
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Revised |
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2016-04-26 12:26 |
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Second Decision |
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2016-04-28 09:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-05-04 18:32 |
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Articles in Press |
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2016-05-04 18:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-05-23 16:20 |
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Publish the Manuscript Online |
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2016-06-02 15:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Basic Study |
| Article Title |
Dominating expression of negative regulatory factors downmodulates major histocompatibility complex Class-Ⅱ expression on dendritic cells in chronic hepatitis C infection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shallu Tomer, Yogesh K Chawla, Ajay Duseja and Sunil K Arora |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Council of Scientific and Industrial Research |
27 (0262) 12/EMR-II |
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| Corresponding Author |
Sunil K Arora, MSc, PhD, MNAMS, Professor, Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. arora.sunil@pgimer.edu.in
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| Key Words |
Dendritic cells; Hepatitis C; Non-responders; Negative regulators; major histocompatibility complex Class-Ⅱ genes |
| Core Tip |
The study was aimed to understand the mechanisms of dendritic cells dysfunction during chronic hepatitis C (CHC) infection. The findings highlight the association between different immune response genes and viral persistence in non-responders to antiviral therapy. Up regulation of negative regulators and down-regulation of molecules involved with antigen presentation seems to associate with non-responsiveness to antiviral therapy. Some novel pathways can be targeted to achieve better management of CHC patients.
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| Publish Date |
2016-06-02 15:26 |
| Citation |
Tomer S, Chawla YK, Duseja A, Arora SK. Dominating expression of negative regulatory factors downmodulates major histocompatibility complex Class-Ⅱ expression on dendritic cells in chronic hepatitis C infection. World J Gastroenterol 2016; 22(22): 5173-5182 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i22/5173.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i22.5173 |
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