| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Retrospective Study |
| Article Title |
Helical tomotherapy and volumetric modulated arc therapy: New therapeutic arms in the breast cancer radiotherapy
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Olivier Lauche, Youlia M Kirova, Pascal Fenoglietto, Emilie Costa, Claire Lemanski, Celine Bourgier, Olivier Riou, David Tiberi, Francois Campana, Alain Fourquet and David Azria |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Youlia M Kirova, MD, Chief of breast cancer research and treatment in the Department of Radiation Oncology, Institut Curie, 26, rue d’Ulm, 75005 Paris, France. youlia.kirova@curie.fr |
| Key Words |
Three-dimensional conformal radiotherapy; Intensity modulated radiation therapy; Toxicity; Helical tomotherapy; Volumetric modulated arc therapy; Breast cancer radiotherapy |
| Core Tip |
Using conventional techniques in breast and nodes irradiation, there could be suboptimal target coverage or great dose exposure to the normal structures. Our study suggests that helical tomotherapy (HT) and volumetric modulated arc therapy (VMAT) plans provide excellent target volume coverage and reduces high doses to organs at risk with an acceptable acute toxicity. At the same time, HT and VMAT deliver lower doses to larger volumes of normal tissues, su-ggesting in some cases an increased risk of second cancer. Nevertheless, the risk to benefit ratio seems to be in favour of HT and VMAT as opposed to three-dimensional conformal radiation therapy in com?plex target volumes, such as funnel chest, tumor in the inner quadrant when internal mammary chain and tumor bed boost are indicated, large breast size or unfavourable cardiac anatomy. |
| Publish Date |
2016-08-26 08:31 |
| Citation |
Lauche O, Kirova YM, Fenoglietto P, Costa E, Lemanski C, Bourgier C, Riou O, Tiberi D, Campana F, Fourquet A, Azria D. Helical tomotherapy and volumetric modulated arc therapy: New therapeutic arms in the breast cancer radiotherapy. World J Radiol 2016; 8(8): 735-742 |
| URL |
http://www.wjgnet.com/1949-8470/full/v8/i8/735.htm |
| DOI |
http://dx.doi.org/10.4329/wjr.v8.i8.735 |
