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Articles Published Processes
9/27/2016 1:42:00 PM | Browse: 1257 | Download: 2648
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Received |
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2016-02-25 09:24 |
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Peer-Review Started |
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2016-02-27 13:50 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-05-13 17:02 |
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Revised |
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2016-06-02 10:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2016-07-20 17:03 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2016-08-01 15:58 |
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Articles in Press |
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2016-08-01 15:58 |
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Edit the Manuscript by Language Editor |
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2016-08-04 07:16 |
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Typeset the Manuscript |
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2016-09-22 18:52 |
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Publish the Manuscript Online |
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2016-09-27 13:42 |
| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Minireviews |
| Article Title |
Evaluation of DNA synthesis with carbon-11-labeled
4′-thiothymidine
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jun Toyohara |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Japan Society for the Promotion of Science |
25293271 |
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| Corresponding Author |
Jun Toyohara, PhD, Theme Leader, Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015,
Japan. toyohara@pet.tmig.or.jp
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| Key Words |
4′-[methyl-11C]-thiothymidine; DNA synthesis; Cell proliferation; Tumor; Positron emission tomography |
| Core Tip |
There is a continuous demand to measure in situ DNA synthesis rates in living human cancer. The thymidine derivative 4′-[methyl-11C] thiothymidine (11C-4DST) has the potential to visualize in vivo DNA synthesis rates with positron emission tomography (PET). To confirm whether 11C-4DST is a valid DNA synthesis marker, clinical and basic research is being conducted at several PET centers in Japan, European Union, and the United States. This mini-review sum-marizes the progress of recent studies involving the in vivo imaging of cancer DNA synthesis using 11C-4DST PET.
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| Publish Date |
2016-09-27 13:42 |
| Citation |
Toyohara J. Evaluation of DNA synthesis with carbon-11-labeled 4′-thiothymidine. World J Radiol 2016; 8(9): 799-808 |
| URL |
http://www.wjgnet.com/1949-8470/full/v8/i9/799.htm |
| DOI |
http://dx.doi.org/10.4329/wjr.v8.i9.799 |
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