Publication Name	World Journal of Gastroenterology
Manuscript ID	2521
Country	Germany

Received	2013-02-26 09:11
Peer-Review Started	2013-02-26 16:27
To Make the First Decision	2013-03-18 15:50
Return for Revision	2013-06-05 09:05
Revised
Second Decision	2013-09-17 09:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-17 11:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-08 11:45
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany
Manuscript Source	Invited Manuscript
All Author List	Hans Scherübl, Brigitte Streller, Roland Stabenow, Hermann Herbst, Michael Höpfner, Christoph Schwertner, Joachim Steinberg, Jan Eick, Wanda Ring, Krishna Tiwari and Sören M Zappe
Funding Agency and Grant Number
Corresponding Author	Dr. Hans Scherübl, Professor, Klinik für Gastroenterologie, GI Onkologie und Infektiologie, Vivantes Klinikum Am Urban, Akademisches Lehrkrankenhaus der Charité Dieffenbachstrasse 1, 10967 Berlin, Germany. hans.scheruebl@vivantes.de
Key Words	Neuroendocrine; Tumor; Epidemiology; Gastrinoma; Insulinoma; Endoscopy; German history; Reunification; Second malignancy
Core Tip	Modern endoscopic and radiological tumor imaging have been implicated in the rise of the incidence of detected neuroendocrine tumors (NET) in Western countries. The particularities of German history, which resulted in two German states with two different health care systems from 1949-1989, allowed to study the epidemiological changes of NET in Germany on the background of two health care systems in 1949-1989. The number of detected gastroenteropancreatic-NET increased about 5-fold between 1976 and 2006. Most likely, the general availability of endoscopy after German reunification contributed to the major rise in frequency of detected rectal, gastric and duodenal NET in the new federal states of reunified Germany.
Publish Date	2014-01-20 16:41
Citation	Scherübl H, Streller B, Stabenow R, Herbst H, Höpfner M, Schwertner C, Steinberg J, Eick J, Ring W, Tiwari K, Zappe SM. Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany. World J Gastroenterol 2013; 19(47): 9012-9019
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/9012.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.9012

Full Article (PDF)	WJG-19-9012.pdf
Manuscript File	2521-Review.docx
Answering Reviewers	2521-Answering reviewers.pdf
Copyright License Agreement	2521-Copyright assignment.pdf
Peer-review Report	2521-Peer reviews.pdf
Scientific Editor Work List	2521-Scientific editor work list.doc