Publication Name	World Journal of Diabetes
Manuscript ID	25554
Country	India

Received	2016-03-17 10:46
Peer-Review Started	2016-03-18 17:58
To Make the First Decision	2016-05-17 13:46
Return for Revision	2016-05-19 10:10
Revised	2016-05-26 09:12
Second Decision	2016-06-27 17:04
Accepted by Journal Editor-in-Chief	2016-06-28 15:24
Accepted by Executive Editor-in-Chief	2016-07-13 13:56
Articles in Press	2016-07-13 13:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-05 08:26
Publish the Manuscript Online	2016-08-09 11:33

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Basic Study
Article Title	Increased fecal viral content associated with obesity in mice
Manuscript Source	Invited Manuscript
All Author List	Hariom Yadav, Shalini Jain, Ravinder Nagpal and Francesco Marotta
Funding Agency and Grant Number
Corresponding Author	Hariom Yadav, PhD, Scientist, Rama­lingaswami Fellow, Department of Nutritional Biote­chnology, National Agri-Food Biotechnology Institute, C-127, Industrial Area, Phase 8, Mohali, Punjab 160071, India. yadavhariom@gmail.com
Key Words	Obesity; Gut; Microbiome; Virome; DNA; RNA; Virus; Fat mass
Core Tip	Gut microbiome is known for major con-stituents of bacterial population, and their association with obesity, but microbes like viruses are majorly neglected. Our investigation on the basis of hypothesis that viruses are an important part of microbial world, and found in substantial numbers into human gut, we investigated whether viral content have any correlation with obesity in mice models. Interestingly, we found that DNA and RNA viral fecal content was significantly increased in obese mice as compared to normal. This suggests that viral population may have role to regulate host metabolism and might impact obesity prevalence via alteration of gut microbiome composition. Our findings open a new area of research to explore the role of gut virome in obesity.
Publish Date	2016-08-09 11:33
Citation	Yadav H, Jain S, Nagpal R, Marotta F. Increased fecal viral content associated with obesity in mice. World J Diabetes 2016; 7(15): 316-320
URL	http://www.wjgnet.com/1948-9358/full/v7/i15/316.htm
DOI	http://dx.doi.org/10.4239/wjd.v7.i15.316

Full Article (PDF)	WJD-7-316.pdf
Full Article (Word)	WJD-7-316.doc
Manuscript File	25554-Review.docx
Answering Reviewers	25554-Answering reviewers.pdf
Audio Core Tip	25554-Audio core tip.mp3
Biostatistics Review Certificate	25554-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	25554-Conflict-of-interest statement.pdf
Copyright License Agreement	25554-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	25554-Institutional animal care and use committee statement.pdf
Peer-review Report	25554-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	25554-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	25554-Scientific misconduct check.pdf
Scientific Editor Work List	25554-Scientific editor work list.pdf