Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	2563
Country	Japan

Received	2013-02-28 14:26
Peer-Review Started	2013-03-01 14:49
To Make the First Decision	2013-03-11 15:00
Return for Revision	2013-03-14 09:30
Revised	2013-03-27 19:41
Second Decision	2013-05-17 14:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-05-18 00:21
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-05-31 14:59
Publish the Manuscript Online	2013-06-09 20:30

ISSN	1948-5190 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Youngest case of an early gastric cancer after successful eradication therapy
Manuscript Source	Invited Manuscript
All Author List	Hironori Konuma, Ichiro Konuma, Kuangi Fu, Satoshi Yamada, Yutaka Suzuki and Akihisa Miyazaki
Funding Agency and Grant Number
Corresponding Author	Kuangi Fu, MD, PhD, Department of Gastroenterology, Juntendo Univerity Nerima Hospital, 3-1-10 Nerimatakanodai, Nerima, Tokyo 177-8521, Japan. fukuangi@hotmail.com
Key Words	Early gastric cancer; Helicobacter pylori; Eradication therapy; Undifferentiated adenocarcinoma; Intestinal-type adenocarcinoma; Point of no return theory
Core Tip	Although, earlier eradication of Helicobacter pylori (H. pylori) is considered to be more effective for prevention of gastric cancer by inhibiting the progression of mucosal atrophy, this youngest case developed an invasive gastric cancer with nodal involvement. From the viewpoint of the “point of no return” theory, future research should focus on the appropriate time of life at which to treat ideal candidates who would benefit from preventive eradication therapy. At present, it appears that cure of H. pylori infection still cannot prevent all gastric cancers, clinical studies are needed to clarify how to follow up patients after successful eradication therapy.
Publish Date	2013-06-09 20:30
Citation	Konuma H, Konuma I, Fu K, Yamada S, Suzuki Y, Miyazaki A. Youngest case of an early gastric cancer after successful eradication therapy. World J Gastrointest Endosc 2013; 5(6): 300-303
URL	http://www.wjgnet.com/1948-5190/full/v5/i6/300.htm
DOI	http://dx.doi.org/10.4253/wjge.v5.i6.300

Full Article (PDF)	WJGE-5-300.pdf
Manuscript File	2563-Review.doc
Answering Reviewers	2563-Answering reviewers.doc
Copyright License Agreement	2563-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2563-Language certificate.doc
Peer-review Report	2563-Peer review(s).pdf
Scientific Editor Work List	2563-Scientific editor work list.doc