Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	25734
Country	Brazil

Received	2016-03-21 09:05
Peer-Review Started	2016-03-23 10:28
To Make the First Decision	2016-04-15 08:26
Return for Revision	2016-04-20 10:54
Revised	2016-04-26 10:21
Second Decision	2016-06-27 17:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-13 14:12
Articles in Press	2016-07-13 14:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-26 18:15
Publish the Manuscript Online	2016-09-12 14:59

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection
Manuscript Source	Invited Manuscript
All Author List	Vitor Arantes, Noriya Uedo, Moises Salgado Pedrosa and Yasuhiko Tomita
Funding Agency and Grant Number
Corresponding Author	Vitor Arantes, MD, MSc, PhD, Endoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Hospital Mater Dei Contorno, Rua Florália 18, apt. 1201, Anchieta, Belo Horizonte 30130-100, Brazil. arantesvitor@ufmg.br
Key Words	Endoscopic submucosal dissection; Early gastric cancer; Endoscopic treatment; Healing; Scar
Core Tip	Endoscopic submucosal dissection is the treat-ment of choice for superficial gastric neoplasms. After curative endoscopic submucosal dissection (ESD), post-operative scar is expected to look consolidated and homogeneous. We describe a series of 14 patients that underwent curative gastric ESD with R0 resection and surprisingly developed an aberrant polypoid nodule at the ESD scar. We denominated this new entity as polypoid nodule scar (PNS). It is noteworthy that PNS occurred only after ESD undertaken for tumors located in the antrum. We reviewed the hypothesis and pathogenic factors that could explain the occurrence of this unusual phenomenon, and discuss propositions about patient’s postoperative clinical management.
Publish Date	2016-09-12 14:59
Citation	Arantes V, Uedo N, Pedrosa MS, Tomita Y. Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection. World J Gastrointest Endosc 2016; 8(17): 628-634
URL	http://www.wjgnet.com/1948-5190/full/v8/i17/628.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i17.628

Full Article (PDF)	WJGE-8-628.pdf
Full Article (Word)	WJGE-8-628.doc
Manuscript File	25734-Review.docx
Answering Reviewers	25734-Answering reviewers.pdf
Audio Core Tip	25734-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	25734-Conflict-of-interest statement.pdf
Copyright License Agreement	25734-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160320190614.docx
Institutional Review Board Approval Form or Document	25734-Institutional review board statement.pdf
Peer-review Report	25734-Peer-review(s).pdf
Scientific Misconduct Check	25734-Scientific misconduct check.pdf
Scientific Editor Work List	25734-Scientific editor work list.pdf