Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	25981
Country	Japan

Received	2016-03-28 16:07
Peer-Review Started	2016-03-29 08:50
To Make the First Decision	2016-05-17 12:19
Return for Revision	2016-05-18 11:12
Revised	2016-06-01 10:13
Second Decision	2016-06-13 16:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-06-29 09:56
Articles in Press	2016-06-29 09:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-16 17:47
Publish the Manuscript Online	2016-08-26 14:15

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Can the prognosis of colorectal cancer be improved by surgery?
Manuscript Source	Invited Manuscript
All Author List	Yasumasa Takii, Satoshi Maruyama and Hitoshi Nogami
Funding Agency and Grant Number	Funding Agency Grant Number National Cancer Research and Development Fund 26-A-4
Corresponding Author	Yasumasa Takii, Niigata Cancer Center Hospital, 15-3 Kawagishi-cho 2-chome, Chuo-ku, Niigata 951-8566, Japan. takii@niigata-cc.jp
Key Words	Colorectal cancer; General surgery; No-touch isolation technique; Circulating tumor cells; Randomized controlled trial
Core Tip	Currently, we are conducting a multicenter randomized controlled trial to confirm the efficacy of the no-touch isolation technique (NTIT) in patients with colorectal cancer. A previous controlled prospective trial was not able to confirm the clinical benefit of NTIT, as it had an insufficient sample size and many patients were lost to follow-up. However, basic and clinical studies have supported the use of NTIT for treating colorectal cancer. The present review serves as a preface to our trial, as it provides background information on whether the prognosis of colorectal cancer is improved by surgery.
Publish Date	2016-08-26 14:15
Citation	Takii Y, Maruyama S, Nogami H. Can the prognosis of colorectal cancer be improved by surgery? World J Gastrointest Surg 2016; 8(8): 574-577
URL	http://www.wjgnet.com/1948-9366/full/v8/i8/574.htm
DOI	http://dx.doi.org/10.4240/wjgs.v8.i8.574

Full Article (PDF)	WJGS-8-574.pdf
Full Article (Word)	WJGS-8-574.doc
Manuscript File	25981-Review.docx
Answering Reviewers	25981-Answering reviewers.pdf
Audio Core Tip	25981-Audio core rip.mp3
Clinical Trial Registration Statement	DeclarationOf_HelsinkiConformation_Statement_20160327103105.pdf
Conflict-of-Interest Disclosure Form	25981-Conflict-of-interest statement.pdf
Copyright License Agreement	25981-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	25981-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	25981-Language certificate.pdf
Peer-review Report	25981-Peer-review(s).pdf
Scientific Misconduct Check	25981-Scientific misconduct check.pdf
Scientific Editor Work List	25981-Scientific editor work list.pdf