Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	26157
Country	Italy

Received	2016-03-30 10:21
Peer-Review Started	2016-04-04 18:53
To Make the First Decision	2016-05-23 10:02
Return for Revision	2016-05-25 19:36
Revised	2016-06-17 02:17
Second Decision	2016-09-12 09:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-09-22 14:03
Articles in Press	2016-09-22 14:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-14 19:17
Publish the Manuscript Online	2016-11-23 10:09

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Review
Article Title	Pre-operative clinical and instrumental factors as antireflux surgery outcome predictors
Manuscript Source	Invited Manuscript
All Author List	Salvatore Tolone, Giorgia Gualtieri, Edoardo Savarino, Marzio Frazzoni, Nicola de Bortoli, Manuele Furnari, Giuseppina Casalino, Simona Parisi, Vincenzo Savarino and Ludovico Docimo
Funding Agency and Grant Number
Corresponding Author	Salvatore Tolone, MD, PhD, Second University of Naples, Division of General and Bariatric Surgery, Via Pansini 5, 80131 Naples, Italy. salvatore.tolone@unina2.it
Key Words	Gastroesophageal reflux disease; Antireflux surgery; Outcome predictors; Fundoplication; Nissen; Laparoscopy; High resolution manometry; Impedance-pH monitoring
Core Tip	Fundoplication is currently the most commonly performed antireflux operation for management of gastroesophageal reflux disease (GERD). Outcomes described in current literature following laparoscopic fundoplication indicate that it is highly effective for treatment of GERD. However it is still unclear which factors, clinical or instrumental, are able to predict a good outcome after surgery. Anatomical conditions seem to not be a risk factor for poor outcome. The predictability of success following laparoscopic fundoplication seems to be directly proportional to the degree of certainty that gastroesophageal reflux is the underlying cause of the patient’s complaints. Thus, performing an accurate pre-operative clinical and instrumental evaluation is mandatory.
Publish Date	2016-11-23 10:09
Citation	Tolone S, Gualtieri G, Savarino E, Frazzoni M, de Bortoli N, Furnari M, Casalino G, Parisi S, Savarino V, Docimo L. Pre-operative clinical and instrumental factors as antireflux surgery outcome predictors. World J Gastrointest Surg 2016; 8(11): 719-728
URL	http://www.wjgnet.com/1948-9366/full/v8/i11/719.htm
DOI	http://dx.doi.org/10.4240/wjgs.v8.i11.719

Full Article (PDF)	WJGS-8-719.pdf
Full Article (Word)	WJGS-8-719.doc
Manuscript File	26157-Review.docx
Answering Reviewers	26157-Answering reviewers.pdf
Audio Core Tip	26157-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	26157-Conflict-of-interest statement.pdf
Copyright License Agreement	26157-Copyright assignment.pdf
Peer-review Report	26157-Peer-review(s).pdf
Scientific Misconduct Check	26157-Scientific misconduct check.pdf
Scientific Editor Work List	26157-Scientific editor work list.pdf