Publication Name	World Journal of Gastroenterology
Manuscript ID	26191
Country	South Korea

Received	2016-03-30 09:32
Peer-Review Started	2016-04-05 10:50
To Make the First Decision	2016-05-12 15:35
Return for Revision	2016-05-13 17:28
Revised	2016-06-02 20:27
Second Decision	2016-06-14 17:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-06-29 09:40
Articles in Press	2016-06-29 09:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-02 13:50
Publish the Manuscript Online	2016-08-15 10:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Virology
Manuscript Type	Topic Highlights
Article Title	Roles of hepatocyte nuclear factors in hepatitis B virus infection
Manuscript Source	Invited Manuscript
All Author List	Doo Hyun Kim, Hong Seok Kang and Kyun-Hwan Kim
Funding Agency and Grant Number	Funding Agency Grant Number Konkuk University in 2016
Corresponding Author	Dr. Kyun-Hwan Kim, Department of Pharmacology, School of Medicine, Konkuk University, Seoul 143-701, South Korea. khkim10@kku.ac.kr
Key Words	Hepatitis B virus; Hepatocyte nuclear factor; Covalently closed circular DNA; Replication
Core Tip	Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease and death worldwide. Persistent HBV infection is a major risk factor for chronic hepatitis and is the leading cause of liver disease, including cirrhosis and hepatocellular carcinoma. In the HBV life cycle, hepatocyte nuclear factors (HNFs) play critical roles in covalently closed circular DNA transcription. Control of HNF expression and function could regulate HBV replication. Therefore, understanding the upstream cellular factors or signals involved in the regulation of HNFs is important for controlling HBV replication.
Publish Date	2016-08-15 10:30
Citation	Kim DH, Kang HS, Kim KH. Roles of hepatocyte nuclear factors in hepatitis B virus infection. World J Gastroenterol 2016; 22(31): 7017-7029
URL	http://www.wjgnet.com/1007-9327/full/v22/i31/7017.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i31.7017

Full Article (PDF)	WJG-22-7017.pdf
Full Article (Word)	WJG-22-7017.doc
Manuscript File	26191-Review.docx
Answering Reviewers	26191-Answering reviewers.pdf
Audio Core Tip	26191-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26191-Conflict-of-interest statement.pdf
Copyright License Agreement	26191-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	26191-Language certificate.pdf
Peer-review Report	26191-Peer-review(s).pdf
Scientific Misconduct Check	26191-Scientific misconduct check.pdf
Scientific Editor Work List	26191-Scientific editor work list.pdf