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12/14/2016 9:26:00 AM | Browse: 470 | Download: 552
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 26650
Country/Territory Canada
2016-04-20 12:14
Peer-Review Started
2016-04-20 16:59
To Make the First Decision
2016-06-06 10:35
Return for Revision
2016-06-12 15:38
2016-07-15 01:36
Second Decision
2016-08-30 11:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-08 17:02
Articles in Press
2016-09-08 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-12-02 17:40
Publish the Manuscript Online
2016-12-14 09:26
ISSN 1948-5190 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Identification of factors associated with sedation tolerance in 5000 patients undergoing outpatient colonoscopy: Canadian tertiary center experience
Manuscript Source Unsolicited Manuscript
All Author List Alexandra Shingina, George Ou, Oliver Takach, Sigrid Svarta, Ricky Kwok, Jessica Tong, Kieran Donaldson, Eric Lam and Robert Enns
Funding Agency and Grant Number
Corresponding Author Robert Enns, MD, Division of Gastroen­terology, Saint Paul Hospital, 770-1190 Hornby Street, Vancouver V6Z 2K5, Canada. rob.enns@ubc.ca
Key Words Colonoscopy; Sedation; Sedation tolerance; Fentanyl; Midazolam; Predictive model
Core Tip This manuscript explores patient specific characteristics that are associated with increased sedation tolerance based on retrospective review of 5000 patients that underwent outpatient colonoscopies. Using a logistic regression analysis, we developed a predictive model that can identify patients requiring higher than usual sedation doses using pre-procedurally available patient parameters. The final prediction model that includes age, indication for the procedure, medication/substance use, previous surgeries yielded an area under the curve of 0.76 for Fentanyl ≥ 100 mcg and Midazolam ≥ 3 mg. This modelling could help optimize periprocedural planning and potentially identify patients who would benefit from alternative sedation methods, e.g., propofol.
Publish Date 2016-12-14 09:26
Citation Shingina A, Ou G, Takach O, Svarta S, Kwok R, Tong J, Donaldson K, Lam E, Enns R. Identification of factors associated with sedation tolerance in 5000 patients undergoing outpatient colonoscopy: Canadian tertiary center experience. World J Gastrointest Endosc 2016; 8(20): 770-776
URL http://www.wjgnet.com/1948-5190/full/v8/i20/770.htm
DOI http://dx.doi.org/10.4253/wjge.v8.i20.770
Full Article (PDF) WJGE-8-770.pdf
Full Article (Word) WJGE-8-770.doc
Manuscript File 26650-Review.docx
Answering Reviewers 26650-Answering reviewers.pdf
Audio Core Tip 26650-Audio core tip.mp3
Biostatistics Review Certificate Biostatistics_Statement_20160420004816.pdf
Conflict-of-Interest Disclosure Form 26650-Conflict-of-interest statement.pdf
Copyright License Agreement 26650-Copyright assignment.pdf
Data Sharing Statement 26650-Data sharing statement.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160420004813.docx
Institutional Review Board Approval Form or Document 26650-Institutional review board statement.pdf
Supplementary Material 26650-Supplementary material.pdf
Peer-review Report 26650-Peer-review(s).pdf
Scientific Misconduct Check 26650-Scientific misconduct check.pdf
Scientific Editor Work List 26650-Scientific editor work list.pdf