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Articles Published Processes
9/23/2016 3:41:00 PM | Browse: 1133 | Download: 1954
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Received |
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2016-04-29 17:17 |
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Peer-Review Started |
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2016-05-03 11:04 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-06-17 16:23 |
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Revised |
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2016-06-26 10:49 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2016-08-08 15:30 |
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Second Decision by Editor-in-Chief |
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2016-08-08 17:33 |
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Final Decision by Editorial Office Director |
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2016-08-18 11:53 |
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Articles in Press |
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2016-08-18 11:53 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-09-18 21:32 |
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Publish the Manuscript Online |
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2016-09-23 15:41 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Updates on antibody-mediated rejection in intestinal transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Guo-Sheng Wu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81570588 |
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| Corresponding Author |
Guo-Sheng Wu, MD, PhD, Division of Gastrointestinal Surgery, Xijing Hospital of Digestive Diseases, the Fourth Military Medical University, #127 Changle West Rd, Xi’an 710032, Shannxi Province,
China. guosheng_w@yahoo.com
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| Key Words |
Intestinal transplantation; Antibody-mediated rejection; Hyperacute rejection; Chronic rejection; Donor-specific antibodies; C4d deposition; Outcomes |
| Core Tip |
Antibody-mediated rejection (ABMR) has increasingly surfaced as an important cause of allograft loss after intestinal transplantation. The presence of donor-specific antibodies (DSAs) should alert the clinician of the increased risk of ABMR. The avoidance of a known donor-specific antibody target at the time of transplant remains a primary preventive strategy. The development of newly-formed DSAs usually portends a poor prognosis with an increased risk of refractory acute rejection, chronic rejection, and allograft loss. The better understanding of mechanisms of antibody-mediated graft injury, establishment of the diagnostic criteria, and optimal management of these antibodies may improve clinical outcomes of intestine transplants.
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| Publish Date |
2016-09-23 15:41 |
| Citation |
Wu GS. Updates on antibody-mediated rejection in intestinal transplantation. World J Transplant 2016; 6(3): 564-572 |
| URL |
http://www.wjgnet.com/2220-3230/full/v6/i3/564.htm |
| DOI |
http://dx.doi.org/10.5500/wjt.v6.i3.564 |
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