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Articles Published Processes
10/25/2016 8:46:00 AM | Browse: 1530 | Download: 2375
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Received |
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2016-05-08 13:37 |
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Peer-Review Started |
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2016-05-09 20:16 |
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To Make the First Decision |
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2016-06-06 11:05 |
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Return for Revision |
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2016-06-13 16:40 |
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Revised |
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2016-07-18 00:00 |
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Second Decision |
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2016-08-30 11:56 |
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Accepted by Journal Editor-in-Chief |
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2016-08-30 20:34 |
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Accepted by Executive Editor-in-Chief |
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2016-09-18 14:48 |
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Articles in Press |
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2016-09-18 14:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-10-18 14:37 |
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Publish the Manuscript Online |
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2016-10-25 08:46 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Retrospective study of the associations between hepatitis C virus infection and metabolic factors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shira Yair-Sabag, Elchanan Nussinson, Ofir Ben-Assuli, Fahmi Shibli, Azmi Shahbari and Shira Zelber-Sagi |
| Funding Agency and Grant Number |
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| Corresponding Author |
Elchanan Nussinson, MD, Gastroenterology Institute, Emek Medical Center, Duchifat 7 St, Afula 18742, Israel. elchanann@gmail.com |
| Key Words |
Hepatitis C virus; Type 2 diabetes mellitus; Antiviral therapy; Sustained viral response; Metabolic syndrome; Hepatic steatosis; Peg interferon alpha; Ribavirin; Direct acting antiviral agents |
| Core Tip |
Hepatitis C virus (HCV) is associated with a unique metabolic syndrome (MS) type: Insulin resistance with type 2 diabetes mellitus (T2DM), hypocho-lesterolemia, and liver steatosis. We retrospectively investigated the association between MS components and HCV infection, including antiviral therapy response, for 119 patients infected with HCV treated with inter-feron alpha and ribavirin. After long-term follow-up, de novo T2DM incidence significantly decreased, and triglyceride levels significantly increased in treatment responders. Only steatosis tended to affect treatment response. The association between HCV and lipid metabolic pathways may be important even with new direct antiviral agents. Patients infected with HCV should be screened for T2DM. |
| Publish Date |
2016-10-25 08:46 |
| Citation |
Yair-Sabag S, Nussinson E, Ben-Assuli O, Shibli F, Shahbari A, Zelber-Sagi S. Retrospective study of the associations between hepatitis C virus infection and metabolic factors. World J Hepatol 2016; 8(30): 1269-1278 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i30/1269.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i30.1269 |
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