Publication Name	World Journal of Gastroenterology
Manuscript ID	27092
Country	Italy

Received	2016-05-10 09:21
Peer-Review Started	2016-05-11 14:58
First Decision by Editorial Office Director
Return for Revision	2016-05-30 18:26
Revised	2016-06-07 17:21
Publication Fee Transferred
Second Decision by Editor	2016-06-21 10:10
Second Decision by Editor-in-Chief	2016-06-22 17:02
Final Decision by Editorial Office Director	2016-06-28 15:10
Articles in Press	2016-06-28 15:11
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-05 13:10
Publish the Manuscript Online	2016-08-15 10:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Metabolic aspects of adult patients with nonalcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Ludovico Abenavoli, Natasa Milic, Laura Di Renzo, Tomislav Preveden, Milica Medić-Stojanoska and Antonino De Lorenzo
Funding Agency and Grant Number
Corresponding Author	Ludovico Abenavoli, MD, PhD, Department of Health Sciences, University Magna Graecia, Campus Germaneto, Viale Europa, 88100 Catanzaro, Italy. l.abenavoli@unicz.it
Key Words	nonalcoholic fatty liver disease; nonalcoholic steatohepatitis; insulin resistance; obesity; metabolic syndrome
Core Tip	In the recent years it has been reported that nonalcoholic fatty liver disease (NAFLD) pathogenesis is related with a multi hits theory where insulin resistance has a central role and renders hepatocytes susceptible to other pathogenetic factors including oxidative stress, dysregulation of cytokines production; increased intestinal permeability, intestinal dysbiosis, inflammation and fibrosis. In this context, numerous metabolic alterations are associated with NAFLD in the adult patients.
Publish Date	2016-08-15 10:30
Citation	Abenavoli L, Milic N, Di Renzo L, Preveden T, Medić-Stojanoska M, De Lorenzo A. Metabolic aspects of adult patients with nonalcoholic fatty liver disease. World J Gastroenterol 2016; 22(31): 7006-7016
URL	http://www.wjgnet.com/1007-9327/full/v22/i31/7006.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i31.7006

Full Article (PDF)	WJG-22-7006.pdf
Full Article (Word)	WJG-22-7006.doc
Manuscript File	27092-Review.docx
Answering Reviewers	27092-Answering reviewers.pdf
Audio Core Tip	27092-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	27092-Conflict-of-interest statement.pdf
Copyright License Agreement	27092-Copyright assignment.pdf
Peer-review Report	27092-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27092-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27092-Scientific misconduct check.pdf