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Articles Published Processes
10/20/2016 5:06:00 PM | Browse: 1220 | Download: 2955
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Received |
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2016-06-20 10:52 |
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Peer-Review Started |
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2016-06-20 16:27 |
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To Make the First Decision |
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2016-07-29 16:27 |
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Return for Revision |
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2016-08-02 09:22 |
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Revised |
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2016-08-23 17:36 |
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Second Decision |
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2016-09-12 16:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-09-14 13:34 |
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Articles in Press |
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2016-09-14 13:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-09-23 16:45 |
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Typeset the Manuscript |
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2016-10-13 11:54 |
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Publish the Manuscript Online |
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2016-10-20 17:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Predicting malignant transformation of esophageal squamous cell lesions by combined biomarkers in an endoscopic screening program
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao Zhang, Hao Li, Qing Ma, Fang-Yan Yang and Tao-Yu Diao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
3057160 |
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| Corresponding Author |
Hao Li, MD, Vice Professor of Medicine, Tumor Center, Qilu Hospital of Shandong University, No. 107 Wenhuaxi Road, Jinan 250012, Shandong Province,
China. haoli2003611@163.com
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| Key Words |
Esophageal squamous cell cancer; Esophageal squamous cell dysplasia; p53; Carcinoembryonic antigen; CA19-9; Immunohistochemistry; Prediction |
| Core Tip |
Immunohistochemical detection of p53, carcinoembryonic antigen (CEA) and CA19-9 proteins was carried out in patients with basal cell hyperplasia, low-grade dysplasia, high-grade dysplasia, invasive cancer, and normal controls from an area with a high incidence of esophageal lesions. Our data suggest that p53, CEA, and CA19-9 protein expression correlated with the stages of esophageal carcinogenesis. In an endoscopic screening program, the expression of these three biomarkers will be a useful panel for identifying high-risk patients with precancerous lesions, and the results will provide a basis for targeted prevention in a high-incidence area of esophageal carcinoma.
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| Publish Date |
2016-10-20 17:06 |
| Citation |
Zhang H, Li H, Ma Q, Yang FY, Diao TY. Predicting malignant transformation of esophageal squamous cell lesions by combined biomarkers in an endoscopic screening program. World J Gastroenterol 2016; 22(39): 8770-8778 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i39/8770.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i39.8770 |
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