Publication Name	World Journal of Gastroenterology
Manuscript ID	27230
Country	China

Received	2016-05-18 16:44
Peer-Review Started	2016-05-19 09:21
To Make the First Decision	2016-06-13 13:52
Return for Revision	2016-06-13 14:13
Revised	2016-06-22 15:01
Second Decision	2016-06-28 09:04
Accepted by Journal Editor-in-Chief	2016-06-28 15:54
Accepted by Executive Editor-in-Chief	2016-07-06 18:33
Articles in Press	2016-07-06 18:33
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-07-16 01:38
Typeset the Manuscript	2016-07-20 19:09
Publish the Manuscript Online	2016-07-29 20:32

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Basic Study
Article Title	Alterations in gut microbiota during remission and recurrence of diabetes after duodenal-jejunal bypass in rats
Manuscript Source	Unsolicited Manuscript
All Author List	Ming-Wei Zhong, Shao-Zhuang Liu, Guang-Yong Zhang, Xiang Zhang, Teng Liu and San-Yuan Hu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81471019 (to Hu SY) National Natural Science Foundation of China 81300286 (to Liu SZ) National Natural Science Foundation of China 81370496 (to Zhang GY) Taishan Scholar Foundation
Corresponding Author	San-Yuan Hu, Professor, Department of General Surgery, Qilu Hospital of Shandong University, No. 107, Wenhua Xi Road, Jinan 250012, Shandong Province, China. husanyuan1962@hotmail.com
Key Words	Duodenal-jejunal bypass; Gut microbiota; Diabetes recurrence; Lipopolysaccharide; Total bile acids
Core Tip	To determine the alteration in gut microbiota during diabetes recurrence after the performance of duodenal-jejunal bypass (DJB), high-fat diet (HFD)-fed and low-dose streptozotocin-injected diabetic rats received DJB. We used postoperative HFD to induce diabetes recurrence. Relative abundance of Firmicutes in diabetes-recurrence rats is lower than that in diabetes-remission rats, whereas higher relative abundance of Bacteroidetes and Escherichia coli is observed in diabetes-recurrence rats. Alterations in gut microbiota may cause diabetes to reappear postoperatively by influencing levels of serum lipopoly-saccharide and total bile acids, which have links with low-grade inflammation and glycolipid metabolism in diabetes.
Publish Date	2016-07-29 20:32
Citation	Zhong MW, Liu SZ, Zhang GY, Zhang X, Liu T, Hu SY. Alterations in gut microbiota during remission and recurrence of diabetes after duodenal-jejunal bypass in rats. World J Gastroenterol 2016; 22(29): 6706-6715
URL	http://www.wjgnet.com/1007-9327/full/v22/i29/6706.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i29.6706

Full Article (PDF)	WJG-22-6706.pdf
Full Article (Word)	WJG-22-6706.doc
Manuscript File	27230-Review.docx
Answering Reviewers	27230-Answering reviewers.pdf
Audio Core Tip	27230-Audio core tip.mp3
Biostatistics Review Certificate	27230-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	27230-Conflict-of-interest statement.pdf
Copyright License Agreement	27230-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	27230-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	27230-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	27230-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	27230-Language certificate.pdf
Peer-review Report	27230-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	27230-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	27230-Scientific misconduct check.pdf
Scientific Editor Work List	27230-Scientific editor work list.pdf