Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	27255
Country	Australia

Received	2016-05-19 17:19
Peer-Review Started	2016-05-20 14:06
To Make the First Decision	2016-06-06 10:45
Return for Revision	2016-06-06 11:49
Revised	2016-06-23 21:02
Second Decision	2016-07-15 16:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-22 12:09
Articles in Press	2016-07-22 12:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-01 16:05
Publish the Manuscript Online	2016-08-07 21:31

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Infectious Diseases
Manuscript Type	Retrospective Study
Article Title	Potential carrier priming effect in Australian infants after 7-valent pneumococcal conjugate vaccine introduction
Manuscript Source	Invited Manuscript
All Author List	Mohamed Tashani, Sanjay Jayasinghe, Zitta B Harboe, Harunor Rashid and Robert Booy
Funding Agency and Grant Number
Corresponding Author	Mohamed Tashani, DCH, MBBCH, MPH, MHM, MIPH, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, the Children’s Hospital at Westmead, Locked Bag 4001, Sydney 2145, Australia. mohamed.tashani@health.nsw.gov.au
Key Words	Carrier priming; Conjugate vaccine; Infant; Invasive pneumococcal disease
Core Tip	With the inclusion of newer conjugate vaccines with higher number of serotypes in the immunisation schedule, literature suggests that prior immunisation with tetanus/diphtheria-containing vaccines could enhance the immunogenicity of subsequently admi-nistered glycoconjugate vaccine, a phenomenon known as “carrier priming”. This analysis provides evidence of substantial clinical protection ensued after one dose of 7-valent pneumococcal conjugate vaccine as result of carrier priming. This phenomenon could be imple-mented to enhance the immunogenicity of conjugate vaccines among vulnerable populations such as infants in resource-poor settings, travellers, immigrants and refugees.
Publish Date	2016-08-07 21:31
Citation	Tashani M, Jayasinghe S, Harboe ZB, Rashid H, Booy R. Potential carrier priming effect in Australian infants after 7-valent pneumococcal conjugate vaccine introduction. World J Clin Pediatr 2016; 5(3): 311-318
URL	http://www.wjgnet.com/2219-2808/full/v5/i3/311.htm
DOI	http://dx.doi.org/10.5409/wjcp.v5.i3.311

Full Article (PDF)	WJCP-5-311.pdf
Full Article (Word)	WJCP-5-311.doc
Manuscript File	27255-Review.docx
Answering Reviewers	27255-Answering reviewers.pdf
Audio Core Tip	27255-Audio core tip.wav
Biostatistics Review Certificate	27255-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	27255-Conflict-of-interest statement.pdf
Copyright License Agreement	27255-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	27255-Institutional review board statement.pdf
Peer-review Report	27255-Peer-review(s).pdf
Scientific Misconduct Check	27255-Scientific misconduct check.pdf
Scientific Editor Work List	27255-Scientific editor work list.pdf