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9/19/2016 2:54:00 PM | Browse: 1007 | Download: 1276
Publication Name World Journal of Psychiatry
Manuscript ID 27320
Country/Territory Israel
Received
2016-05-24 09:20
Peer-Review Started
2016-05-25 09:22
To Make the First Decision
2016-07-04 15:43
Return for Revision
2016-07-06 08:32
Revised
2016-07-21 19:16
Second Decision
2016-07-28 14:52
Accepted by Journal Editor-in-Chief
2016-07-29 06:37
Accepted by Company Editor-in-Chief
2016-08-08 14:38
Articles in Press
2016-08-08 14:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-09-13 13:18
Publish the Manuscript Online
2016-09-19 14:59
ISSN 2220-3206 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Behavioral Sciences
Manuscript Type Review
Article Title Gene environment interaction in periphery and brain converge to modulate behavioral outcomes: Insights from the SP1 transient early in life interference rat model
Manuscript Source Invited Manuscript
All Author List Eyal Asor and Dorit Ben-Shachar
Funding Agency and Grant Number
Corresponding Author Dorit Ben-Shachar, Professor, Laboratory of Psychobiology, Department of Psychiatry, Rambam Medical Center and B. Rappaport Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion, PO Box 9649, Haifa 31096, Israel. shachar@tx.technion.ac.il
Key Words Gene-environmental interaction; Specificity protein 1; Mithramycin; Stress; Animal-model; Essential amino acids; Tryptophan; Insulin
Core Tip We review the main theoretical and practical concepts in the research of gene environment interaction. We present a novel approach to study gene environment interaction in which a brief post-natal interference with the expression of multiple genes by inhibiting the activity of the ubiquitous transcription factor specificity protein 1 is followed by later-in-life exposure of rats to stress. Finally, we discuss the role of peripheral processes in behavioral responses, demonstrating how specific behavioral patterns are linked to modulations in interwoven brain and body physiological processes due to gene and environmental changes.
Publish Date 2016-09-19 14:59
Citation Asor E, Ben-Shachar D. Gene environment interaction in periphery and brain converge to modulate behavioral outcomes: Insights from the SP1 transient early in life interference rat model. World J Psychiatr 2016; 6(3): 294-302
URL http://www.wjgnet.com/2220-3206/full/v6/i3/294.htm
DOI http://dx.doi.org/10.5498/wjp.v6.i3.294
Full Article (PDF) WJP-6-294.pdf
Full Article (Word) WJP-6-294.doc
Manuscript File 27320-Review.docx
Answering Reviewers 27320-Answering reviewers.pdf
Audio Core Tip 27320-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 27320-Conflict-of-interest statement.pdf
Copyright License Agreement 27320-Copyright assignment.pdf
Peer-review Report 27320-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 27320-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 27320-Scientific misconduct check.pdf
Scientific Editor Work List 27320-Scientific editor work list.pdf