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Articles Published Processes
11/4/2016 10:35:00 AM | Browse: 1169 | Download: 2133
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Received |
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2016-05-29 13:25 |
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Peer-Review Started |
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2016-05-29 16:58 |
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To Make the First Decision |
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2016-07-29 15:15 |
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Return for Revision |
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2016-07-29 18:41 |
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Revised |
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2016-08-19 19:14 |
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Second Decision |
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2016-09-02 18:04 |
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Accepted by Journal Editor-in-Chief |
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2016-09-04 17:45 |
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Accepted by Executive Editor-in-Chief |
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2016-09-09 10:22 |
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Articles in Press |
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2016-09-09 10:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-10-31 18:42 |
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Publish the Manuscript Online |
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2016-11-04 10:35 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Safe and effective sofosbuvir-based therapy in patients with mental health disease on hepatitis C virus treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lydia Shuk Yee Tang, Jack Masur, Zayani Sims, Amy Nelson, Anu Osinusi, Anita Kohli, Sarah Kattakuzhy, Michael Polis and Shyam Kottilil |
| Funding Agency and Grant Number |
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| Corresponding Author |
Shyam Kottilil, MD, PhD, Professor of Medicine, Institute of Human Virology, Division of Infectious Diseases, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, MD 21201,
United States. skottilil@ihv.umaryland.edu |
| Key Words |
Sofosbuvir; Direct acting antivirals; Directly acting antiviral; Hepatitis C; Mental health disease; Depression; Interferon; Beck’s Depression Inventory |
| Core Tip |
The prevalence of mental health disease (MHD) among patients with chronic hepatitis C virus (HCV) can be high. However, patients with MHD may be marginalized with respect to HCV therapy and MHD is one of the most frequently cited reason for exclusion from HCV therapy. HCV therapy has evolved from interferon-based to directly acting antiviral (DAA)-based therapy with excellent tolerability and efficacy. Our study found that baseline MHD did not impact efficacy nor treatment adherence to sofosbuvir-based therapy. Furthermore, we found that Becks Depression Inven-tory scores improved with sofosbuvir-based therapy, suggesting that HCV treatment with the newer DAA therapies may have additional mental health benefits. |
| Publish Date |
2016-11-04 10:35 |
| Citation |
Tang LSY, Masur J, Sims Z, Nelson A, Osinusi A, Kohli A, Kattakuzhy S, Polis M, Kottilil S. Safe and effective sofosbuvir-based therapy in patients with mental health disease on hepatitis C virus treatment. World J Hepatol 2016; 8(31): 1318-1326 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i31/1318.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i31.1318 |
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