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Publication Name World Journal of Hematology
Manuscript ID 2744
Country of Manuscript Source Japan
Received
2013-03-12 08:45
Peer-Review Started
2013-03-12 15:53
To Make the First Decision
2013-04-16 09:22
Return for Revision
2013-04-20 20:03
Revised
2013-05-10 16:40
Second Decision
2013-06-06 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-06-06 13:02
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-07-15 15:41
Publish the Manuscript Online
2013-07-25 22:33
ISSN 2218-6204 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Hematology
Manuscript Type Case Report
Article Title Management of adult Langerhans cell histiocytosis based on the characteristic clinical features
Manuscript Source Invited Manuscript
All Author List Shinsaku Imashuku, Chihiro Shimazaki, Arinobu Tojo, Toshihiko Imamura and Akira Morimoto
Funding Agency and Grant Number
Corresponding author Shinsaku Imashuku, MD, Consultant, Division of Hematology, Takasago-seibu Hospital, 1-10-41 Nakasuji, Takasago 676-0812, Japan. shinim95@mbox.kyoto-inet.or.jp
Keywords Langerhans cell histiocytosis; Adult; Immuno-chemotherapy; 2-chlorodeoxyadenosine; Childbirth
Core Tip Clinical features and treatment in a total of 18 adult patients with langerhans cell histiocytosis (LCH) were reviewed. We found two major groups regarding the initial symptoms; one was central diabetes insipidus and other endocrine symptoms (n = 9) and the other bone diseases (n = 8; 1 skull, 4 spinal and 3 multiple). We also recognized the correlation between pregnancy/childbirth and LCH in 4 patients. Based on the clinical features and outcomes, early diagnosis and rapid introduction of appropriate treatment are essential, in order to overcome the problems relevant to adult LCH.
Publish Date 2013-07-25 22:33
Citation Imashuku S, Shimazaki C, Tojo A, Imamura T, Morimoto A. Management of adult Langerhans cell histiocytosis based on the characteristic clinical features. World J Hematol 2013; 2(3): 89-98
Url http://www.wjgnet.com/2218-6204/full/v2/i3/89.htm
DOI http://dx.doi.org/10.5315/wjh.v2.i3.89
Full Article (PDF) WJH-2-89.pdf
Manuscript File 2744-Review.doc
Answering Reviewers 2744-Answering reviewers.docx
Copyright License Agreement 2744-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 2744-Language certificate.pdf
Peer-review Report 2744-Peer review(s).pdf
Scientific Editor Work List 2744-Scientific editor work list.doc