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11/25/2016 9:02:00 AM | Browse: 478 | Download: 569
Publication Name World Journal of Hepatology
Manuscript ID 27576
Country/Territory Thailand
Received
2016-06-07 10:08
Peer-Review Started
2016-06-07 11:51
To Make the First Decision
2016-08-10 14:55
Return for Revision
2016-08-11 09:58
Revised
2016-08-21 17:20
Second Decision
2016-10-13 12:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-10-24 15:22
Articles in Press
2016-10-24 15:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-21 08:30
Publish the Manuscript Online
2016-11-25 09:02
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Prospective Study
Article Title Elevation of serum urokinase plasminogen activator receptor and liver stiffness in postoperative biliary atresia
Manuscript Source Invited Manuscript
All Author List Wanvisa Udomsinprasert, Sittisak Honsawek, Napaphat Jirathanathornnukul, Voranush Chongsrisawat and Yong Poovorawan
Funding Agency and Grant Number
Corresponding Author Sittisak Honsawek, MD, PhD, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama IV Road, Patumwan, Bangkok 10330, Thailand. sittisak.h@chula.ac.th
Key Words Biliary atresia; Jaundice; Liver stiffness; Severity; Urokinase plasminogen activator receptor
Core Tip Urokinase plasminogen activator receptor (uPAR) is known to be a substantial factor in the etiopathogenesis of hepatic inflammation and liver fibrogenesis. This study is the first to show that circulating uPAR is more elevated in biliary atresia (BA) children than in control subjects, and that circulating uPAR is correlated with the degree of jaundice and liver fibrosis in biliary atresia. Elevated serum uPAR is positively correlated with the severity of liver stiffness in postKasai BA children. Hence, serum uPAR could be used as a biological parameter indicating the pro-gression and prognosis of liver fibrosis in BA children.
Publish Date 2016-11-25 09:02
Citation Udomsinprasert W, Honsawek S, Jirathanathornnukul N, Chongsrisawat V, Poovorawan Y. Elevation of serum urokinase plasminogen activator receptor and liver stiffness in postoperative biliary atresia. World J Hepatol 2016; 8(33): 1471-1477
URL http://www.wjgnet.com/1948-5182/full/v8/i33/1471.htm
DOI http://dx.doi.org/10.4254/wjh.v8.i33.1471
Full Article (PDF) WJH-8-1471.pdf
Full Article (Word) WJH-8-1471.doc
Manuscript File 27576-Review.doc
Answering Reviewers 27576-Answering reviewers.pdf
Audio Core Tip 27576-Audio core tip.mp3
Biostatistics Review Certificate 27576-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 27576-Conflict-of-interest statement.pdf
Copyright License Agreement 27576-Copyright assignment.pdf
Data Sharing Statement 27576-Data sharing statement.pdf
Institutional Review Board Approval Form or Document 27576-Institutional review board statement.pdf
Scientific Research Process 27576-Scientific research process.pdf
Peer-review Report 27576-Peer-review(s).pdf
Scientific Misconduct Check 27576-Scientific misconduct check.pdf
Scientific Editor Work List 27576-Scientific editor work list.pdf