Publication Name	World Journal of Hepatology
Manuscript ID	27576
Country	Thailand

Received	2016-06-07 10:08
Peer-Review Started	2016-06-07 11:51
To Make the First Decision	2016-08-10 14:55
Return for Revision	2016-08-11 09:58
Revised	2016-08-21 17:20
Second Decision	2016-10-13 12:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-24 15:22
Articles in Press	2016-10-24 15:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-21 08:30
Publish the Manuscript Online	2016-11-25 09:02

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Elevation of serum urokinase plasminogen activator receptor and liver stiffness in postoperative biliary atresia
Manuscript Source	Invited Manuscript
All Author List	Wanvisa Udomsinprasert, Sittisak Honsawek, Napaphat Jirathanathornnukul, Voranush Chongsrisawat and Yong Poovorawan
Funding Agency and Grant Number
Corresponding Author	Sittisak Honsawek, MD, PhD, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama IV Road, Patumwan, Bangkok 10330, Thailand. sittisak.h@chula.ac.th
Key Words	Biliary atresia; Jaundice; Liver stiffness; Severity; Urokinase plasminogen activator receptor
Core Tip	Urokinase plasminogen activator receptor (uPAR) is known to be a substantial factor in the etiopathogenesis of hepatic inflammation and liver fibrogenesis. This study is the first to show that circulating uPAR is more elevated in biliary atresia (BA) children than in control subjects, and that circulating uPAR is correlated with the degree of jaundice and liver fibrosis in biliary atresia. Elevated serum uPAR is positively correlated with the severity of liver stiffness in postKasai BA children. Hence, serum uPAR could be used as a biological parameter indicating the pro-gression and prognosis of liver fibrosis in BA children.
Publish Date	2016-11-25 09:02
Citation	Udomsinprasert W, Honsawek S, Jirathanathornnukul N, Chongsrisawat V, Poovorawan Y. Elevation of serum urokinase plasminogen activator receptor and liver stiffness in postoperative biliary atresia. World J Hepatol 2016; 8(33): 1471-1477
URL	http://www.wjgnet.com/1948-5182/full/v8/i33/1471.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i33.1471

Full Article (PDF)	WJH-8-1471.pdf
Full Article (Word)	WJH-8-1471.doc
Manuscript File	27576-Review.doc
Answering Reviewers	27576-Answering reviewers.pdf
Audio Core Tip	27576-Audio core tip.mp3
Biostatistics Review Certificate	27576-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	27576-Conflict-of-interest statement.pdf
Copyright License Agreement	27576-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	27576-Institutional review board statement.pdf
Peer-review Report	27576-Peer-review(s).pdf
Scientific Misconduct Check	27576-Scientific misconduct check.pdf
Scientific Editor Work List	27576-Scientific editor work list.pdf