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Articles Published Processes
9/19/2016 2:54:00 PM | Browse: 988 | Download: 1544
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Received |
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2016-06-21 08:29 |
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Peer-Review Started |
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To Make the First Decision |
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Return for Revision |
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Revised |
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Second Decision |
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2016-06-27 16:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-07-13 13:49 |
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Articles in Press |
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2016-07-13 13:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-09-13 13:18 |
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Publish the Manuscript Online |
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2016-09-19 14:59 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Case Control Study |
| Article Title |
Voxel-based magnetic resonance imaging investigation of poor and preserved clinical insight in people with schizophrenia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Adegboyega Sapara, Dominic H Ffytche, Michael A Cooke, Steven CR Williams and Veena Kumari |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Wellcome Trust, United Kingdom |
067427 |
| Wellcome Trust, United Kingdom |
072298 |
| Biomedical Research Centre for Mental Health at the Institute of Psychiatry, Psychology and Neuroscience King’s College London, and the South London and Maudsley NHS Foundation Trust, United Kingdom |
to Kumari V |
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| Corresponding Author |
Veena Kumari, PhD, Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, De Crespigny Park, London SE5 8AF, United Kingdom. veena.kumari@kcl.ac.uk |
| Key Words |
Psychosis; Insight; Grey matter volumes; Fronto-temporal; Neural networks; Birchwood insight scale |
| Core Tip |
Poor clinical insight is the most prevalent symptom in patients with schizophrenia and is of growing importance due to its direct association with poor clinical outcomes, such as frequent relapses and hospital admissions. This study identified significantly reduced fronto-temporal, parahippocampal, occipital and cerebellar grey matter volumes in Insight- patients relative to both Insight+ patients and healthy controls. The involvement of multiple brain areas and corresponding neural networks supports the theory that clinical insight, as a neurological function, is not confined to specific neuroanatomical regions but probably a function of a complex neurocognitive interplay with contributions from multiple neural networks. |
| Publish Date |
2016-09-19 14:59 |
| Citation |
Sapara A, Ffytche DH, Cooke MA, Williams SCR, Kumari V. Voxel-based magnetic resonance imaging investigation of poor and preserved clinical insight in people with schizophrenia. World J Psychiatr 2016; 6(3): 311-321 |
| URL |
http://www.wjgnet.com/2220-3206/full/v6/i3/311.htm |
| DOI |
http://dx.doi.org/10.5498/wjp.v6.i3.311 |
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