| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Basic Study |
| Article Title |
Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Nada M Melhem, Hassan Zaraket, Khalil Kreidieh, Zeinab Ali, Moza Hammadi, Soha Ghanem, Farah Hajar, Amjad Haidar, Adlette Inati, Mariam Rajab, Hassan Fakhouri, Bassam Ghanem, Ghassan Baasiri and Ghassan Dbaibo |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University Review Board Grant, American University of Beirut |
102852 |
| Investigator-initiated research grant from Merck Sharpe and Dohme (MSD) |
|
|
| Corresponding Author |
Nada M Melhem, PhD, Associate Professor, Medical Laboratory Sciences Program, Faculty of Health Sciences, American University of Beirut, PO Box 11-0236 Riad El Solh, 325 Van Dyck Hall, Beirut 1107-2020, Lebanon. melhemn@aub.edu.lb |
| Key Words |
Norovirus; Reverse transcription polymerase chain reaction; Sequencing; Norovirus genogroup Ⅰ; Norovirus genogroup Ⅱ; Lebanon |
| Core Tip |
We report the results of a large study of norovirus (NoV)-associated gastroenteritis among children aged < 5 years in Lebanon. The majority of viral gastroenteritis cases were attributable to NoV GⅡ.4, which is compatible with results reported worldwide. Our data support a peak incidence in July, while reports from other countries show peaks during the cold months. We report NoV A JB-15/KOR/2008 GⅡ.4 Apeldoorn 2008-like variant strain circulating in 2011. This strain was replaced between 2012 and 2013 by a variant sharing homology with the Sydney/NSW0514/2012/AUS GⅡ.4 Sydney 2012 and Sydney 2012/FRA GⅡ.4 strains. |
| Publish Date |
2016-12-26 19:13 |
| Citation |
Melhem NM, Zaraket H, Kreidieh K, Ali Z, Hammadi M, Ghanem S, Hajar F, Haidar A, Inati A, Rajab M, Fakhouri H, Ghanem B, Baasiri G, Dbaibo G. Clinical and epidemiological characteristics of norovirus gastroenteritis among hospitalized children in Lebanon. World J Gastroenterol 2016; 22(48): 10557-10565 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i48/10557.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i48.10557 |
