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9/11/2014 8:39:00 PM | Browse: 333 | Download: 217
Publication Name World Journal of Gastroenterology
Manuscript ID 2839
Country/Territory Italy
Received
2013-03-19 09:41
Peer-Review Started
2013-03-20 09:26
To Make the First Decision
2013-04-03 09:13
Return for Revision
2013-04-15 17:10
Revised
2013-04-16 21:01
Second Decision
2013-05-07 17:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-08 09:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-12-08 14:59
Publish the Manuscript Online
2013-12-18 10:00
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Autobiography
Article Title Dietary-suppression of hepatic lipogenic enzyme expression in intact male transgenic mice
Manuscript Source Invited Manuscript
All Author List Maria Notarnicola, Maria Gabriella Caruso, Angela Tafaro, Valeria Tutino, Giusy Bianco, Mario Minoia and Antonio Francavilla
Funding Agency and Grant Number
Corresponding author Maria Notarnicola, ScD, Laboratory of Nutritional Biochemistry, National Institute for Digestive Diseases, Via della Resistenza, Castellana Grotte, 70013 Bari, Italy. maria.notarnicola@irccsdebellis.it
Keywords Lipogenic enzymes; Liver; Markers of cell proliferation; Transgenic mice; Dietary treatment
Core Tip The olive oil diet significantly reduces the enzymatic activities, as well as the expression of hepatic cell cycle related genes. The addition of drugs as lovastatin and orlistat to olive oil diet more down-regulated the studied lipogenic enzymes, demonstrating that the inhibition of these enzymes with natural components of diet could have a potential benefit in association with canonical chemical substances to counteract hepatic cell proliferation in mice.
Publish Date 2013-12-18 10:00
Citation Notarnicola M, Caruso MG, Tafaro A, Tutino V, Bianco G, Minoia M, Francavilla A. Dietary-suppression of hepatic lipogenic enzyme expression in intact male transgenic mice. World J Gastroenterol 2013; 19(46): 8671-8677
Url http://www.wjgnet.com/1007-9327/full/v19/i46/8671.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i46.8671
Full Article (PDF) WJG-19-8671.pdf
Manuscript File 2839-Review.docx
Answering Reviewers 2839-Answering reviewers.pdf
Copyright License Agreement 2839-Copyright assignment.pdf
Peer-review Report 2839-Peer reviews.pdf
Scientific Editor Work List 2839-Scientific editor work list.doc