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Articles Published Processes
9/11/2014 8:39:00 PM | Browse: 822 | Download: 620
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Received |
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2013-03-19 09:41 |
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Peer-Review Started |
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2013-03-20 09:26 |
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To Make the First Decision |
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2013-04-03 09:13 |
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Return for Revision |
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2013-04-15 17:10 |
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Revised |
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2013-04-16 21:01 |
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Second Decision |
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2013-05-07 17:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-05-08 09:30 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-12-08 14:59 |
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Publish the Manuscript Online |
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2013-12-18 10:00 |
Category |
Oncology |
Manuscript Type |
Autobiography |
Article Title |
Dietary-suppression of hepatic lipogenic enzyme expression in intact male transgenic mice
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Manuscript Source |
Invited Manuscript |
All Author List |
Maria Notarnicola, Maria Gabriella Caruso, Angela Tafaro, Valeria Tutino, Giusy Bianco, Mario Minoia and Antonio Francavilla |
Funding Agency and Grant Number |
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Corresponding Author |
Maria Notarnicola, ScD, Laboratory of Nutritional Biochemistry, National Institute for Digestive Diseases, Via della Resistenza, Castellana Grotte, 70013 Bari, Italy. maria.notarnicola@irccsdebellis.it |
Key Words |
Lipogenic enzymes; Liver; Markers of cell proliferation; Transgenic mice; Dietary treatment |
Core Tip |
The olive oil diet significantly reduces the enzymatic activities, as well as the expression of hepatic cell cycle related genes. The addition of drugs as lovastatin and orlistat to olive oil diet more down-regulated the studied lipogenic enzymes, demonstrating that the inhibition of these enzymes with natural components of diet could have a potential benefit in association with canonical chemical substances to counteract hepatic cell proliferation in mice.
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Publish Date |
2013-12-18 10:00 |
Citation |
Notarnicola M, Caruso MG, Tafaro A, Tutino V, Bianco G, Minoia M, Francavilla A. Dietary-suppression of hepatic lipogenic enzyme expression in intact male transgenic mice. World J Gastroenterol 2013; 19(46): 8671-8677 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i46/8671.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i46.8671 |
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