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Articles Published Processes
12/27/2016 8:31:00 AM | Browse: 1526 | Download: 2450
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Received |
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2016-07-01 09:24 |
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Peer-Review Started |
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2016-07-03 14:57 |
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To Make the First Decision |
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2016-08-04 16:26 |
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Return for Revision |
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2016-08-05 12:08 |
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Revised |
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2016-09-16 04:03 |
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Second Decision |
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2016-10-28 11:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-11-02 16:14 |
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Articles in Press |
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2016-11-02 16:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-12-19 08:43 |
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Publish the Manuscript Online |
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2016-12-27 08:31 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sarah Logan, Alison Rodger, Laura Maynard-Smith, James O’Beirne, Thomas Fernandez, Filippo Ferro, Colette Smith and Sanjay Bhagani |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| British HIV Association Research Award |
2009-£7800 in total awarded |
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| Corresponding Author |
Dr. Sanjay Bhagani, Consultant in Infectious Diseases and HIV Medicine, the Ian Charleson Day Centre, Ground Floor, Royal Free London NHS Foundation Trust, Rowland Hill Street, London NW3 2PF,
United Kingdom. s.bhagani@nhs.net |
| Key Words |
Nodular regenerative hyperplasia; Human immunodeficiency virus; Steatosis; Non-cirrhotic portal hypertension; Didanosine |
| Core Tip |
Human immunodeficiency virus positive pa-tients are at increased risk of liver disease. The aetio-logy is often multifactorial and includes exposure to antiretroviral therapy. We used a simple screening stra-tegy based on transient elastography, liver enzymes and ultrasound scan to identify that 2% of asymptomatic patients exposed to Didanosine in a clinical cohort had undiagnosed nodular regenerative hyperplasia. A further 6% had undiagnosed steatosis. Implementation of a screening strategy enables identification of liver disease and initiation of earlier targeted interventions in this high-risk group. |
| Publish Date |
2016-12-27 08:31 |
| Citation |
Logan S, Rodger A, Maynard-Smith L, O’Beirne J, Fernandez T, Ferro F, Smith C, Bhagani S. Prevalence of significant liver disease in human immunodeficiency virus-infected patients exposed to Didanosine: A cross sectional study. World J Hepatol 2016; 8(36): 1623-1628 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i36/1623.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i36.1623 |
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