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10/12/2016 2:18:00 PM | Browse: 1028 | Download: 1723
Publication Name World Journal of Gastroenterology
Manuscript ID 28620
Country China
Received
2016-07-07 09:42
Peer-Review Started
2016-07-07 09:59
To Make the First Decision
2016-08-19 15:10
Return for Revision
2016-08-19 16:02
Revised
2016-08-24 16:22
Second Decision
2016-09-12 13:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-14 13:36
Articles in Press
2016-09-14 13:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-09-27 05:45
Typeset the Manuscript
2016-09-28 16:27
Publish the Manuscript Online
2016-10-12 14:18
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Combination of three-gene immunohistochemical panel and magnetic resonance imaging-detected extramural vascular invasion to assess prognosis in non-advanced rectal cancer patients
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Fu Li, Zheng Jiang, Ying Gao, Chun-Xiang Li and Bao-Zhong Shen
Funding Agency and Grant Number
Corresponding Author Dr. Bao-Zhong Shen, Department of Radiology, The Fourth Affiliated Hospital, Harbin Medical University, 37 Yi Yuan Street, Nan Gang District, Harbin 150001, Heilongjiang Province, China. dr_shenbz@yeah.net
Key Words Rectal cancer; Magnetic resonance imaging; Prognosis; Immunohistochemistry; Extramural vascular invasion
Core Tip Magnetic resonance imaging (MRI) to determine the stage of rectal cancer has been shown to be accurate and reproducible. The patients who showed MRI-detected extramural vascular invasion (EMVI) positivity had worse survival outcomes than those with EMVI negativity. However, the survival rates of patients with an EMVI-positive histology varies dramatically, which suggests that this factor does not relate to each individual tumor in terms of the biology or molecular features. The ideal staging system evolves from the consideration of them and the correlation of the prognosis with patient-specific tumor biomarkers. In this study, we hypothesized that the combination of imaging evidence of EMVI and biomolecular factors could provide additional predictive value in clinical practice, especially for non-advanced cancer patients.
Publish Date 2016-10-12 14:18
Citation Li XF, Jiang Z, Gao Y, Li CX, Shen BZ. Combination of three-gene immunohistochemical panel and magnetic resonance imaging-detected extramural vascular invasion to assess prognosis in non-advanced rectal cancer patients. World J Gastroenterol 2016; 22(38): 8576-8583
URL http://www.wjgnet.com/1007-9327/full/v22/i38/8576.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i38.8576
Full Article (PDF) WJG-22-8576.pdf
Full Article (Word) WJG-22-8576.doc
Manuscript File 28620-Review.docx
Answering Reviewers 28620-Answering reviewers.pdf
Audio Core Tip 28620-Audio core tip.mp3
Biostatistics Review Certificate 28620-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 28620-Conflict-of-interest statement.pdf
Copyright License Agreement 28620-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160707091735.pdf
Institutional Review Board Approval Form or Document 28620-Institutional review board statement.pdf
Peer-review Report 28620-Peer-review(s).pdf
Scientific Misconduct Check 28620-Scientific misconduct check.pdf
Scientific Editor Work List 28620-Scientific editor work list.pdf