Publication Name	World Journal of Gastroenterology
Manuscript ID	28679
Country	Germany

Received	2016-07-11 09:32
Peer-Review Started	2016-07-13 12:31
To Make the First Decision	2016-07-29 16:27
Return for Revision	2016-08-02 17:40
Revised	2016-09-15 00:49
Second Decision	2016-09-30 10:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-10 17:16
Articles in Press	2016-10-10 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-09 15:29
Publish the Manuscript Online	2016-11-12 13:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Review
Article Title	Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases
Manuscript Source	Invited Manuscript
All Author List	Ulrike Billmeier, Walburga Dieterich, Markus F Neurath and Raja Atreya
Funding Agency and Grant Number	Funding Agency Grant Number DFG-CRC1181 C02 International Organization for the Study of Inflammatory Bowel Diseases
Corresponding Author	Raja Atreya, MD, Professor, Medical Clinic 1, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany. raja.atreya@uk-erlangen.de
Key Words	Mucosal immunology; Lamina propria mononuclear cells; Crohn’s disease; Ulcerative colitis; Transmembrane tumor necrosis factor; Apoptosis
Core Tip	To improve the response rates of patients with inflammatory bowel diseases to anti-tumor necrosis factor (TNF) therapy, it is mandatory to understand the pleiotropic effects of these agents. Herein, we overview and discuss several immunological targets of anti-TNF antibody application and highlight the most important findings.
Publish Date	2016-11-12 13:34
Citation	Billmeier U, Dieterich W, Neurath MF, Atreya R. Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases. World J Gastroenterol 2016; 22(42): 9300-9313
URL	http://www.wjgnet.com/1007-9327/full/v22/i42/9300.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i42.9300

Full Article (PDF)	WJG-22-9300.pdf
Full Article (Word)	WJG-22-9300.doc
Manuscript File	28679-Review.docx
Answering Reviewers	28679-Answering reviewers.pdf
Audio Core Tip	28679-Audio core tip.wav
Conflict-of-Interest Disclosure Form	28679-Conflict-of-interest statement.pdf
Copyright License Agreement	28679-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	28679-Grant application form(s).pdf
Peer-review Report	28679-Peer-review(s).pdf
Scientific Misconduct Check	28679-Scientific misconduct check.pdf
Scientific Editor Work List	28679-Scientific editor work list.pdf