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12/14/2016 2:15:00 PM | Browse: 228 | Download: 280
Publication Name World Journal of Transplantation
Manuscript ID 28693
Country of Manuscript Source United States
Received
2016-07-11 08:41
Peer-Review Started
2016-07-11 17:24
To Make the First Decision
2016-09-30 11:20
Return for Revision
2016-09-30 14:22
Revised
2016-10-03 21:24
Second Decision
2016-10-21 10:17
Accepted by Journal Editor-in-Chief
2016-10-24 20:11
Accepted by Company Editor-in-Chief
2016-11-02 16:29
Articles in Press
2016-11-02 16:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-12-05 14:31
Publish the Manuscript Online
2016-12-14 14:32
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Transplantation
Manuscript type Minireviews
Article Title More than skin deep? Potential nicotinamide treatment applications in chronic kidney transplant recipients
Manuscript Source Unsolicited Manuscript
All Author List Andrew G Bostom, Basma Merhi, Joanna Walker and Leslie Robinson-Bostom
Funding Agency and Grant Number
Correspondence To Andrew G Bostom, MD, MS, Associate Professor of Medicine, Research Physician, Division of Hypertension and Kidney Diseases, Department of Medicine, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, United States. abostom@cox.net
Keywords Kidney transplantation; Skin neoplasms; Niacinamide; Phosphorus
Core Tip Our unique review describes promising evidence that oral nicotinamide may have dual therapeutic clinical applications in chronic kidney transplant recipients (KTRs). First, nicotinamide, via its inhibition of sirtuin-mediated enzymatic pathways, may reduce the rate of KTR non-melanoma skin cancers. Second, nicotinamide’s hypophosphatemic effect could lower the rate of cardiorenal outcomes in KTRs. These hypothesized benefits warrant further study in randomized, placebo-controlled trials of nicotinamide treatment with both intermediate, and eventually, hard clinical outcomes.
Publish Date 2016-12-14 14:32
Citation Bostom AG, Merhi B, Walker J, Robinson-Bostom L. More than skin deep? Potential nicotinamide treatment applications in chronic kidney transplant recipients. World J Transplant 2016; 6(4): 658-664
Url http://www.wjgnet.com/2220-3230/full/v6/i4/658.htm
DOI http://dx.doi.org/10.5500/wjt.v6.i4.658
Full Article (PDF) WJT-6-658.pdf
Full Article (Word) WJT-6-658.doc
Manuscript File 28693-Review.docx
Answering Reviewers 28693-Answering reviewers.pdf
Audio Core Tip 28693-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 28693-Conflict-of-interest statement.pdf
Copyright License Agreement 28693-Copyright assignment.pdf
Peer-review Report 28693-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 28693-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 28693-Scientific misconduct check.pdf
Scientific Editor Work List 28693-Scientific editor work list.pdf