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12/20/2016 1:38:00 PM | Browse: 365 | Download: 454
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 28751
Country/Territory Canada
2016-08-04 17:23
Peer-Review Started
2016-08-05 11:49
To Make the First Decision
2016-08-26 08:16
Return for Revision
2016-08-29 16:59
2016-09-07 12:37
Second Decision
2016-09-28 11:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-10-18 17:14
Articles in Press
2016-10-18 17:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-12-15 09:55
Publish the Manuscript Online
2016-12-20 13:39
ISSN 1948-9366 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Report
Article Title Bevacizumab and gastrointestinal bleeding in hereditary hemorrhagic telangiectasia
Manuscript Source Unsolicited Manuscript
All Author List George Ou, Cherry Galorport and Robert Enns
Funding Agency and Grant Number
Corresponding author Robert Enns, MD, FRCPC, Division of Gastroenterology, Department of Medicine, St. Paul’s Hospital, University of British Columbia, Suite 770 - 1190 Hornby Street, Vancouver, BC V6Z 1Y6, Canada. rob.enns@ubc.ca
Keywords Bevacizumab; Vascular endothelial growth factor; Hereditary hemorrhagic telangiectasia; Bleeding; Osler-Weber-Rendu syndrome
Core Tip Management of gastrointestinal (GI) bleeding in patients with hereditary hemorrhagic telangiectasia (HHT) can be challenging when the vascular lesions recur despite repeated endoscopic treatments. There is increasing evidence supporting the use of anti-angio-genesis agents in the management of bleeding in HHT patients. Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has been shown to reduce recurrent epistaxis. This case demonstrates the therapeutic potential of bevacizumab in patients with severe GI bleeding requiring massive transfusions.
Publish Date 2016-12-20 13:39
Citation Ou G, Galorport C, Enns R. Bevacizumab and gastrointestinal bleeding in hereditary hemorrhagic telangiectasia. World J Gastrointest Surg 2016; 8(12): 792-795
Url http://www.wjgnet.com/1948-9366/full/v8/i12/792.htm
DOI http://dx.doi.org/10.4240/wjgs.v8.i12.792
Full Article (PDF) WJGS-8-792.pdf
Full Article (Word) WJGS-8-792.doc
Manuscript File 28751-Review.docx
Answering Reviewers 28751-Answering reviewers.pdf
Audio Core Tip 28751-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 28751-Conflict-of-interest statement.pdf
Copyright License Agreement 28751-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160804131825.docx
Institutional Review Board Approval Form or Document 28751-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20160713150135.docx
Peer-review Report 28751-Peer-review(s).pdf
Scientific Misconduct Check 28751-Scientific misconduct check.pdf
Scientific Editor Work List 28751-Scientific editor work list.pdf