Publication Name	World Journal of Transplantation
Manuscript ID	28777
Country	United Kingdom

Received	2016-07-25 10:57
Peer-Review Started	2016-07-25 15:05
To Make the First Decision	2016-09-02 14:08
Return for Revision	2016-09-13 12:06
Revised	2016-09-23 05:56
Second Decision	2016-11-01 09:44
Accepted by Journal Editor-in-Chief	2016-11-01 23:36
Accepted by Executive Editor-in-Chief	2016-11-17 14:06
Articles in Press	2016-11-17 14:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-05 14:32
Publish the Manuscript Online	2016-12-14 14:32

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Evidence-Based Medicine
Article Title	Corticosteroid minimization in renal transplantation: Careful patient selection enables feasibility
Manuscript Source	Invited Manuscript
All Author List	Georgios Vlachopanos, Julie M Bridson, Ajay Sharma and Ahmed Halawa
Funding Agency and Grant Number
Corresponding Author	Ahmed Halawa, Consultant Transplant Surgeon, Department of Transplantation, Sheffield Teaching Hospitals, Herries Road, Sheffield S5 7AU, United Kingdom. ahmed.halawa@sth.nhs.uk
Key Words	Acute rejection; Corticosteroid withdrawal; Corticosteroid minimization; Corticosteroid avoidance; Immunosuppression; Renal transplantation
Core Tip	Although corticosteroids have been traditional components of immunosuppressive regimens in renal transplantation, corticosteroid minimization strategies are developed in an attempt to mitigate their many side-effects. The benefit from this approach must be balanced against the risk of acute rejection due to insufficient immunosuppression and the potential harm to allograft survival. We present an overview of these strategies and their impact on clinical outcomes analyzing the key clinical trials performed. Furthermore, we focus on patient selection according to the immunological risk and the induction immunosuppression, the principal factors that determine the success of corticosteroid withdrawal and avoidance protocols.
Publish Date	2016-12-14 14:32
Citation	Vlachopanos G, Bridson JM, Sharma A, Halawa A. Corticosteroid minimization in renal transplantation: Careful patient selection enables feasibility. World J Transplant 2016; 6(4): 759-766
URL	http://www.wjgnet.com/2220-3230/full/v6/i4/759.htm
DOI	http://dx.doi.org/10.5500/wjt.v6.i4.759

Full Article (PDF)	WJT-6-759.pdf
Full Article (Word)	WJT-6-759.doc
Manuscript File	28777-Review.docx
Answering Reviewers	28777-Answering reviewers.pdf
Audio Core Tip	28777-Audio core tip.mp3
Biostatistics Review Certificate	28777-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	28777-Conflict-of-interest statement.pdf
Copyright License Agreement	28777-Copyright assignment.pdf
Peer-review Report	28777-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	28777-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	28777-Scientific misconduct check.pdf
Scientific Editor Work List	28777-Scientific editor work list.pdf