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Articles Published Processes
11/12/2016 1:33:00 PM | Browse: 1157 | Download: 2363
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Received |
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2016-07-18 10:07 |
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Peer-Review Started |
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2016-07-18 21:40 |
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To Make the First Decision |
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2016-08-29 08:43 |
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Return for Revision |
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2016-09-02 10:05 |
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Revised |
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2016-09-10 21:09 |
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Second Decision |
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2016-09-30 13:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-10-10 17:32 |
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Articles in Press |
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2016-10-10 17:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-09 15:23 |
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Publish the Manuscript Online |
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2016-11-12 13:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Lymphovascular invasion in more than one-quarter of small rectal neuroendocrine tumors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mi Jung Kwon, Ho Suk Kang, Jae Seung Soh, Hyun Lim, Jong Hyeok Kim, Choong Kee Park, Hye-Rim Park and Eun Sook Nam |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ho Suk Kang, MD, Department of Internal Medicine, Hallym University Sacred Heart Hospital, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, Anyang-si 431-796, South Korea. hskang76@hallym.or.kr |
| Key Words |
Rectum; Neuroendocrine tumor; Lymphatic; Immunohistochemistry; Prognosis |
| Core Tip |
The majority of rectal neuroendocrine tumors (NETs) are small (66%-80% are ≤ 1 cm in diameter) and endoscopic resection techniques have shown successful outcomes. However, lymphovascular inva?sions, a well-established risk factor for lymph node metastasis, are often found at endoscopically resected specimens and there are no definite guidelines about these cases. Therefore, we investigate the frequency and prognostic significance of lymphovascular invasion (LVI) in small endoscopically resected rectal NETs. We found that LVI may be present in a high percentage of small rectal NETs by two histologic methods; hematoxylin and eosin staining and ancillary immunohistochemical staining (D2-40 and Elastica van Gieson). On the other hands, LVI was not associated with lymph node metastasis or recurrence in small rectal NETs (≤ 1 cm) during a 3 year-follow up period. Although our follow-up period was short, but I'm confident in our studies will be the cornerstone of future researches about significance of LVI in small rectal NETs. |
| Publish Date |
2016-11-12 13:34 |
| Citation |
Kwon MJ, Kang HS, Soh JS, Lim H, Kim JH, Park CK, Park HR, Nam ES. Lymphovascular invasion in more than one-quarter of small rectal neuroendocrine tumors. World J Gastroenterol 2016; 22(42): 9400-9410 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i42/9400.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i42.9400 |
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