12/19/2016 8:28:00 PM | Browse: 1180 | Download: 2028
| Publication Name | World Journal of Gastroenterology |
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| Manuscript ID | 29064 |
| Country | Japan |
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| ISSN | 1007-9327 (print) and 2219-2840 (online) |
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| Open Access | This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright | © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Gastroenterology & Hepatology | ||||
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| Manuscript Type | Observational Study | ||||
| Article Title | Relationship between ghrelin, Helicobacter pylori and gastric mucosal atrophy in hemodialysis patients | ||||
| Manuscript Source | Invited Manuscript | ||||
| All Author List | Hitomi Ichikawa, Mitsushige Sugimoto, Yukitoshi Sakao, Shu Sahara, Naro Ohashi, Akihiko Kato, Ken Sugimoto, Takahisa Furuta, Akira Andoh, Tadashi Sakao and Hideo Yasuda | ||||
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| Corresponding Author | Mitsushige Sugimoto, MD, PhD, Division of Digestive Endoscopy, Shiga University of Medical Science Hospital, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan. sugimo@belle.shiga-med.ac.jp | ||||
| Key Words | Acyl-ghrelin; Desacyl-ghrelin; Helicobacter pylori; Hemodialysis; Pepsinogen | ||||
| Core Tip | Ghrelin enhances the orexigenic effect, protein anabolism, anti-inflammatory actions and cardiovascular protection in hemodialysis patients. Helicobacter pylori (H. pylori) infection and gastric mucosal atrophy affect ghrelin level in subjects with normal renal function. However, it is unclear whether ghrelin in hemodialysis patients relates to H. pylori status or gastric mucosal atrophy. This study demonstrated that plasma ghrelin level was associated with endoscopic and serological severity of atrophy related with H. pylori infection in hemodalysis patients. Therefore, eradication therapy of H. pylori before the progression of atrophy might improve ghrelin level associated with nutrition status, such as protein-energy wasting. | ||||
| Publish Date | 2016-12-19 20:29 | ||||
| Citation | Ichikawa H, Sugimoto M, Sakao Y, Sahara S, Ohashi N, Kato A, Sugimoto K, Furuta T, Andoh A, Sakao T, Yasuda H. Relationship between ghrelin, Helicobacter pylori and gastric mucosal atrophy in hemodialysis patients. World J Gastroenterol 2016; 22(47): 10440-10449 | ||||
| URL | http://www.wjgnet.com/1007-9327/full/v22/i47/10440.htm | ||||
| DOI | http://dx.doi.org/10.3748/wjg.v22.i47.10440 |
| Full Article (PDF) | WJG-22-10440.pdf |
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| Full Article (Word) | WJG-22-10440.doc |
| Manuscript File | 29064-Review.docx |
| Answering Reviewers | 29064-Answering reviewers.pdf |
| Audio Core Tip | 29064-Audio core tip.mp3 |
| Biostatistics Review Certificate | 29064-Biostatistics statement.pdf |
| Conflict-of-Interest Disclosure Form | 29064-Conflict-of-interest statement.pdf |
| Copyright License Agreement | 29064-Copyright assignment.pdf |
| Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) | 29064-Grant application form(s).pdf |
| Institutional Review Board Approval Form or Document | 29064-Institutional review board statement.pdf |
| Non-Native Speakers of English Editing Certificate | 29064-Language certificate.pdf |
| Peer-review Report | 29064-Peer-review(s).pdf |
| Journal Editor-in-Chief Review Report | 29064-Journal editor-in-chief review report.pdf |
| Scientific Misconduct Check | 29064-Scientific misconduct check.pdf |
| Scientific Editor Work List | 29064-Scientific editor work list.pdf |