Publication Name	World Journal of Gastroenterology
Manuscript ID	29234
Country	Canada

Received	2016-08-04 09:36
Peer-Review Started	2016-08-05 11:02
To Make the First Decision	2016-09-21 15:16
Return for Revision	2016-09-23 15:49
Revised	2016-11-01 10:29
Second Decision	2016-11-11 14:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-11-16 16:24
Articles in Press	2016-11-16 16:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-12 09:33
Publish the Manuscript Online	2016-12-19 20:29

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease
Manuscript Source	Unsolicited Manuscript
All Author List	Alice Yuxin Wang, Jelena Popov and Nikhil Pai
Funding Agency and Grant Number
Corresponding Author	Nikhil Pai, MD FAAP FRCPC, Assistant Professor, Department of Pediatrics, Division of Pediatric Gastroenterology, McMaster Children’s Hospital, McMaster University, Hamilton, 1280 Main Street West, HSC 3A21, Ontario L8N 3Z5, Canada. pain@mcmaster.ca
Key Words	Inflammatory bowel disease; Microbiome; Microbiota; Fecal microbial transplant; Pediatric; Crohn’s disease; Ulcerative colitis
Core Tip	There is growing interest in fecal microbial transplant (FMT) for the treatment of pediatric inflammatory bowel disease (IBD). The therapeutic potential of bacterial therapies is intriguing. FMT is effective for treating recurrent Clostridium difficile infection, distinct microbial signatures in IBD continue to be described, and patients are increasingly looking for therapeutic options with lower rates of morbidity. This review describes existing adult and pediatric literature on the role of FMT in IBD, features of the IBD microbiome that may be associated with res-ponse, current trials, and the potential challenges and opportunities for the future of FMT in pediatric IBD treatment.
Publish Date	2016-12-19 20:29
Citation	Wang AY, Popov J, Pai N. Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease. World J Gastroenterol 2016; 22(47): 10304-10315
URL	http://www.wjgnet.com/1007-9327/full/v22/i47/10304.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i47.10304

Full Article (PDF)	WJG-22-10304.pdf
Full Article (Word)	WJG-22-10304.doc
Manuscript File	29234-Review.docx
Answering Reviewers	29234-Answering reviewers.pdf
Audio Core Tip	29234-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29234-Conflict-of-interest statement.pdf
Copyright License Agreement	29234-Copyright assignment.pdf
Peer-review Report	29234-Peer-review(s).pdf
Scientific Misconduct Check	29234-Scientific misconduct check.pdf
Scientific Editor Work List	29234-Scientific editor work list.pdf