Publication Name	World Journal of Stem Cells
Manuscript ID	29741
Country	Netherlands

Received	2016-08-26 08:49
Peer-Review Started	2016-08-26 19:03
First Decision by Editorial Office Director
Return for Revision	2016-11-17 08:54
Revised	2016-11-22 20:32
Publication Fee Transferred
Second Decision by Editor	2017-01-04 15:59
Second Decision by Editor-in-Chief	2017-01-05 12:40
Final Decision by Editorial Office Director	2017-01-14 14:35
Articles in Press	2017-01-14 14:35
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-02-17 11:13
Publish the Manuscript Online	2017-02-24 09:00

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Hematology
Manuscript Type	Minireviews
Article Title	Impact of T cells on hematopoietic stem and progenitor cell function: Good guys or bad guys?
Manuscript Source	Invited Manuscript
All Author List	Sulima Geerman and Martijn A Nolte
Funding Agency and Grant Number	Funding Agency Grant Number Landsteiner Foundation for Blood Transfusion Research (www.lsbr.nl) #1014
Corresponding Author	Martijn A Nolte, PhD, Sanquin Research, Department of Hematopoiesis, Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Plesmanlaan 125, 1066CX Amsterdam, The Netherlands. m.nolte@sanquin.nl
Key Words	Hematopoietic stem cells; Hematopoietic stem and progenitor cells; CD8 T cells; Transplantation; Engraftment; Memory T cells; Facilitating cells; Bone marrow
Core Tip	T cells act as a double-edged sword upon allogeneic hematopoietic stem and progenitor cells (HSPC) transplantation, as they support engraftment of HSPCs and provide anti-tumor activity, but are also the cause of graft-vs-host disease (GvHD). Here, we discuss the findings from several studies that have addressed the still enigmatic role of T cells during HSPC transplantation, either in an allogeneic or autologous setting, in mice or men, and with HSPCs derived from bone marrow, peripheral blood or cord blood. We anticipate that a better comprehension of how T cells support HSPC en-graftment may lead to new strategies to optimize HSPCs transplantations and prevent GvHD.
Publish Date	2017-02-24 09:00
Citation	Geerman S, Nolte MA. Impact of T cells on hematopoietic stem and progenitor cell function: Good guys or bad guys? World J Stem Cells 2017; 9(2): 37-44
URL	http://www.wjgnet.com/1948-0210/full/v9/i2/37.htm
DOI	http://dx.doi.org/10.4252/wjsc.v9.i2.37

Full Article (PDF)	WJSC-9-37.pdf
Full Article (Word)	WJSC-9-37.doc
Manuscript File	29741-Review.docx
Answering Reviewers	29741-Answering reviewers.pdf
Audio Core Tip	29741-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29741-Conflict-of-interest statement.pdf
Copyright License Agreement	29741-Copyright assignment.pdf
Peer-review Report	29741-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	29741-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	29741-Scientific misconduct check.pdf
Scientific Editor Work List	29741-Scientific editor work list.pdf