Publication Name	World Journal of Cardiology
Manuscript ID	30016
Country	United States

Received	2016-09-04 14:55
Peer-Review Started	2016-09-07 09:56
To Make the First Decision	2016-09-26 09:00
Return for Revision	2016-09-29 17:17
Revised	2016-11-28 00:00
Second Decision	2016-12-12 08:40
Accepted by Journal Editor-in-Chief	2016-12-13 00:38
Accepted by Executive Editor-in-Chief	2016-12-19 11:08
Articles in Press	2016-12-19 11:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-22 22:21
Publish the Manuscript Online	2017-03-26 19:18

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Pheochromocytoma and stress cardiomyopathy: Insight into pathogenesis
Manuscript Source	Invited Manuscript
All Author List	Sahil Agrawal, Jamshid Shirani, Lohit Garg, Amitoj Singh, Santo Longo, Angelita Longo, Mark Fegley, Lauren Stone, Muhammad Razavi, Nicoleta Radoianu and Sudip Nanda
Funding Agency and Grant Number
Corresponding Author	Sahil Agrawal, MD, Department of Cardiology, St. Luke’s University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, United States. sahilagrawal124@gmail.com
Key Words	Pheochromocytoma; Cardiomyopathy; Stress
Core Tip	A non-ischemic cardiomyopathy (CMP) may be observed in patients with pheochromocytoma and shares several features with takotsubo cardiomyopathy. Although it is believed that pheochromocytoma related CMP is due to the catecholamine excess, the exact pathogenesis is unclear. CMP in pheochromocytoma patients often follows acute stress and while clinical course maybe complicated by acute hemodynamic com-promise, prognosis is good. On the basis of our findings, where 3 of 18 pheochromocytoma patients developed an acute CMP, we suggest that activation of a brain-neural-cardiac axis from acute stress and local release of catecholamines but not chronic catecholamine elevations may likely be responsible for pheo related CMP.
Publish Date	2017-03-26 19:18
Citation	Agrawal S, Shirani J, Garg L, Singh A, Longo S, Longo A, Fegley M, Stone L, Razavi M, Radoianu N, Nanda S. Pheochromocytoma and stress cardiomyopathy: Insight into pathogenesis. World J Cardiol 2017; 9(3): 255-260
URL	http://www.wjgnet.com/1949-8462/full/v9/i3/255.htm
DOI	http://dx.doi.org/10.4330/wjc.v9.i3.255

Full Article (PDF)	WJC-9-255.pdf
Full Article (Word)	WJC-9-255.doc
Manuscript File	30016-Review.docx
Answering Reviewers	30016-Answering reviewers.pdf
Audio Core Tip	30016-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	30016-Conflict-of-interest statement.pdf
Copyright License Agreement	30016-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30016-Institutional review board statement.pdf
Peer-review Report	30016-Peer-review(s).pdf
Scientific Misconduct Check	30016-Scientific misconduct check.pdf
Scientific Editor Work List	30016-Scientific editor work list.pdf