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1/19/2017 11:16:00 AM | Browse: 674 | Download: 859
Publication Name World Journal of Gastroenterology
Manuscript ID 30111
Country/Territory India
Received
2016-09-12 08:54
Peer-Review Started
2016-09-12 20:31
To Make the First Decision
2016-10-10 12:15
Return for Revision
2016-10-13 17:11
Revised
2016-11-15 19:09
Second Decision
2016-12-25 10:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-01-03 12:01
Articles in Press
2017-01-03 12:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-01-08 20:21
Publish the Manuscript Online
2017-01-19 11:16
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Correlation of transient elastography with hepatic venous pressure gradient in patients with cirrhotic portal hypertension: A study of 326 patients from India
Manuscript Source Invited Manuscript
All Author List Ashish Kumar, Noor Muhammad Khan, Shrihari Anil Anikhindi, Praveen Sharma, Naresh Bansal, Vikas Singla and Anil Arora
Funding Agency and Grant Number
Corresponding Author Ashish Kumar, MBBS, MD, DM, Associate Professor, Institute of Liver, Gastroenterology, and Pancreatico-Biliary Sciences, Ganga Ram Institute for Postgraduate Medical Education and Research, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi 110060, India. ashishk10@yahoo.com
Key Words Portal hypertension; cirrhosis; clinically significant portal hypertension; liver stiffness; transient elastography; FibroScan
Core Tip Clinically significant portal hypertension (CSPH), which is defined as hepatic venous pressure gradient (HVPG) ≥ 10 mmHg, causes major complications of cirrhosis. HVPG is invasive, so a non-invasive tool to diagnose CSPH is needed. This study of 326 Indian patients tested the diagnostic accuracy of transient elastography (TE) for detecting CSPH. We observed a significant positive correlation between TE and HVPG (rho 0.361, p < 0.001). The area under the receiver operating characteristic curve for TE in predicting CSPH was 0.740. A cut-off value of TE of 21.6 kPa best predicted CSPH with a positive predictive value of 93%. Thus, TE can be used as a non-invasive modality to assess the degree of portal hypertension.
Publish Date 2017-01-19 11:16
Citation Kumar A, Khan NM, Anikhindi SA, Sharma P, Bansal N, Singla V, Arora A. Correlation of transient elastography with hepatic venous pressure gradient in patients with cirrhotic portal hypertension: A study of 326 patients from India. World J Gastroenterol 2017; 23(4): 687-696
URL http://www.wjgnet.com/1007-9327/full/v23/i4/687.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i4.687
Full Article (PDF) WJG-23-687.pdf
Full Article (Word) WJG-23-687.doc
Manuscript File 30111-Review.docx
Answering Reviewers 30111-Answering reviewers.pdf
Audio Core Tip 30111-Audio core tip.mp3
Biostatistics Review Certificate 30111-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 30111-Conflict-of-interest statement.pdf
Copyright License Agreement 30111-Copyright assignment.pdf
Data Sharing Statement 30111-Data sharing statement.pdf
Institutional Review Board Approval Form or Document 30111-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 30111-Language certificate.pdf
Scientific Research Process 30111-Scientific research process.pdf
Peer-review Report 30111-Peer-review(s).pdf
Scientific Misconduct Check 30111-Scientific misconduct check.pdf
Scientific Editor Work List 30111-Scientific editor work list.pdf