Publication Name	World Journal of Hepatology
Manuscript ID	30178
Country	Germany

Received	2016-09-18 17:33
Peer-Review Started	2016-09-20 08:24
To Make the First Decision	2016-10-21 09:00
Return for Revision	2016-10-21 13:44
Revised	2016-11-09 04:55
Second Decision	2016-11-17 16:50
Accepted by Journal Editor-in-Chief	2016-11-20 18:26
Accepted by Executive Editor-in-Chief	2016-11-29 09:07
Articles in Press	2016-11-29 09:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-01-11 08:34
Publish the Manuscript Online	2017-01-22 08:28

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Retrospective Study
Article Title	Biliary complications following liver transplantation: Single-center experience over three decades and recent risk factors
Manuscript Source	Invited Manuscript
All Author List	Alexander Kaltenborn, André Gutcke, Jill Gwiasda, Jürgen Klempnauer and Harald Schrem
Funding Agency and Grant Number
Corresponding Author	Alexander Kaltenborn, MD, Maj, MC, GAF, Research Fellow, QM and HTA in Transplantation, Core Facility Quality Management and Health Technology Assessment in Transplantation, Integrated Research and Treatment Facility Transplantation (IFB-Tx), Hannover Medical School, Carl-Neuberg Str. 1, 30625 Hannover, Germany. kaltenborn.alexander@mh-hannover.de
Key Words	Biliary complications; Liver transplantation; Prognostic model; Risk factors; Multivariable analyses
Core Tip	This retrospective study investigates the occurrence of biliary complications in a total of 1607 consecutive liver transplant patients throughout three decades. Since introduction of Model of End-Stage Liver Disease (MELD)-based liver allocation, the recipient’s MELD-score at transplantation, the development of he-patic artery thrombosis post-operatively, as well as the donor creatinine prior to explantation were identified as independent risk factors, thus a combination of high recipient MELD-score and impaired donor kidney function should be avoided. Risk is especially increased when post-transplant hepatic artery thrombosis occurs. A prognostic model for the prediction of anastomotic biliary complications was developed and successfully internally validated.
Publish Date	2017-01-22 08:28
Citation	Kaltenborn A, Gutcke A, Gwiasda J, Klempnauer J, Schrem H. Biliary complications following liver transplantation: Single-center experience over three decades and recent risk factors. World J Hepatol 2017; 9(3): 147-154
URL	http://www.wjgnet.com/1948-5182/full/v9/i3/147.htm
DOI	http://dx.doi.org/10.4254/wjh.v9.i3.147

Full Article (PDF)	WJH-9-147.pdf
Full Article (Word)	WJH-9-147.doc
Manuscript File	30178-Review.docx
Answering Reviewers	30178-Answering reviewers.pdf
Audio Core Tip	30178-Audio core tip.m4a
Biostatistics Review Certificate	30178-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30178-Conflict-of-interest statement.pdf
Copyright License Agreement	30178-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160917003031.docx
Institutional Review Board Approval Form or Document	30178-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	30178-Language certificate.pdf
Peer-review Report	30178-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	30178-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	30178-Scientific misconduct check.pdf
Scientific Editor Work List	30178-Scientific editor work list.pdf