Publication Name	World Journal of Nephrology
Manuscript ID	30213
Country	India

Received	2016-09-20 09:47
Peer-Review Started	2016-09-23 11:10
To Make the First Decision	2016-10-20 08:44
Return for Revision	2016-11-02 15:11
Revised	2016-11-10 02:16
Second Decision	2017-03-07 15:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-17 14:12
Articles in Press	2017-03-17 14:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-28 14:46
Publish the Manuscript Online	2017-05-04 18:19

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Retrospective Study
Article Title	Clinicopathological spectrum of snake bite-induced acute kidney injury from India
Manuscript Source	Invited Manuscript
All Author List	Sanjay Vikrant, Ajay Jaryal and Anupam Parashar
Funding Agency and Grant Number
Corresponding Author	Sanjay Vikrant, MD, DM, FISN, Professor, Head, Department of Nephrology, Indira Gandhi Medical College, Himachal Pradesh, Circular Road, Shimla 171001, India. sanjayvikrant@rediffmail.com
Key Words	Acute kidney injury; Acute tubular necrosis; Acute interstitial nephritis; Envenomation; Hemolysis; Renal cortical necrosis; Rhabdomyolysis; Snake bite
Core Tip	Acute kidney injury (AKI) due to snake bite is an important cause of community acquired tropical AKI. Clinicopathological spectrum of snake-induced AKI has changed. Intravascular hemolysis and rhabdomyolysis is common and is the main cause of AKI due to snake bite. AKI is severe and high proportion of patients requires renal replacement therapy. Complications of pneumonia/acute respiratory distress syndrome, seizure/encephalopathy, multi organ failure, the need for intensive care support and a shorter hospital stay are factors associated with mortality. On renal histology acute tubular necrosis and acute interstitial nephritis is common, renal cortical necrosis is rare. Early administration of anti-snake-venom and alkaline diuresis may help in prevention of AKI.
Publish Date	2017-05-04 18:19
Citation	Vikrant S, Jaryal A, Parashar A. Clinicopathological spectrum of snake bite-induced acute kidney injury from India. World J Nephrol 2017; 6(3): 150-161
URL	http://www.wjgnet.com/2220-6124/full/v6/i3/150.htm
DOI	http://dx.doi.org/10.5527/wjn.v6.i3.150

Full Article (PDF)	WJN-6-150.pdf
Full Article (Word)	WJN-6-150.doc
Manuscript File	30213-Review.docx
Answering Reviewers	30213-Answering reviewers.pdf
Audio Core Tip	30213-Audio core tip.m4a
Biostatistics Review Certificate	30213-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	30213-Conflict-of-interest statement.pdf
Copyright License Agreement	30213-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	30213-Institutional review board statement.pdf
Video	Video_20160919224002.tif
Supplementary Material	Supplementary_Material_20160919224828.docx
Peer-review Report	30213-Peer-review(s).pdf
Scientific Misconduct Check	30213-Scientific misconduct check.pdf
Scientific Editor Work List	30213-Scientific editor work list.pdf