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7/12/2017 6:47:21 AM | Browse: 509 | Download: 275
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 30362
Country/Territory United Kingdom
Received
2016-09-29 09:16
Peer-Review Started
2016-10-07 20:45
To Make the First Decision
2016-12-01 14:16
Return for Revision
2016-12-06 19:07
Revised
2017-01-05 18:00
Second Decision
2017-03-15 17:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-24 10:27
Articles in Press
2017-03-24 10:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-04 01:33
Publish the Manuscript Online
2017-07-12 06:47
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Emerging molecular targets and therapy for cholangiocarcinoma
Manuscript Source Invited Manuscript
All Author List Hamzeh Kayhanian, Elizabeth C Smyth and Chiara Braconi
Funding Agency and Grant Number
Corresponding author Dr. Elizabeth C Smyth, Department of Gastrointestinal Oncology, Royal Marsden Hospital, London and Surrey SM2 5PT, United Kingdom. elizabeth.smyth@rmh.nhs.uk
Key Words Cholangiocarcinoma; biliary tract cancer; targeted therapy; immunotherapy; mutation; molecular; microenvironment; stroma; MiRNA
Core Tip Cholangiocarcinoma (CCA) is a clinically challenging malignancy; it is rare, molecularly hetero­genous and associated with a poor prognosis. Here we review recent data on the genomic landscape of CCA and highlight the results of clinical trials using targeted agents and immunotherapy. We find a number of pro­mising therapeutic agents in development and discuss strategies to improve diagnosis and outcomes in this patient group.
Publish Date 2017-07-12 06:47
Citation Kayhanian H, Smyth EC, Braconi C. Emerging molecular targets and therapy for cholangiocarcinoma. World J Gastrointest Oncol 2017; 9(7): 268-280
Url http://www.wjgnet.com/1948-5204/full/v9/i7/268.htm
DOI http://dx.doi.org/10.4251/wjgo.v9.i7.268
Full Article (PDF) WJGO-9-268.pdf
Full Article (Word) WJGO-9-268.doc
Manuscript File 30362-Review.docx
Answering Reviewers 30362-Answering reviewers.pdf
Audio Core Tip 30362-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 30362-Conflict-of-interest statement.pdf
Copyright License Agreement 30362-Copyright assignment.pdf
Peer-review Report 30362-Peer-review(s).pdf
Scientific Misconduct Check 30362-Scientific misconduct check.pdf
Scientific Editor Work List 30362-Scientific editor work list.pdf