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Articles Published Processes
3/24/2017 9:18:00 AM | Browse: 1552 | Download: 3187
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Received |
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2016-09-29 17:27 |
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Peer-Review Started |
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2016-09-30 17:39 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-12-29 11:58 |
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Revised |
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2017-01-06 07:03 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2017-03-02 16:13 |
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Second Decision by Editor-in-Chief |
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2017-03-02 22:58 |
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Final Decision by Editorial Office Director |
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2017-03-13 11:29 |
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Articles in Press |
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2017-03-13 11:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-03-17 17:28 |
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Publish the Manuscript Online |
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2017-03-24 09:18 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mohamed K Shaker, Hanzada I Abdel Fattah, Ghada S Sabbour, Iman F Montasser, Sara M Abdelhakam, Eman El Hadidy, Rehab Yousry and Ahmed K El Dorry |
| Funding Agency and Grant Number |
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| Corresponding Author |
Sara M Abdelhakam, MD, Assistant Professor of Tropical Medicine, Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Khalifa El-Maamon Street, Abbassia, Cairo 11341, Egypt. saratropical@yahoo.com |
| Key Words |
Hepatocellular carcinoma; Hepatitis C virus; annexin A2; Alpha-fetoprotein; Tumor markers |
| Core Tip |
Thirty percent of hepatocellular carcinoma (HCC) patients present with normal serum alpha feto-protein, which highlights the need for new biomarkers for HCC. In the present study, a highly significant diffe-rence was observed among patients with HCC and chronic liver disease as well as controls with regard to serum annexin A2 (ANXA2) levels (130, IQR 15-240; 15, IQR 15-17; and 17, IQR 15-30 ng/ml, respectively). The area under the curve of ANXA2 was 0.865; the cut-off value was 18 ng/mL with a diagnostic sensitivity of 74% and specificity of 88%. Thus, ANXA2 may serve as a useful biomarker for the early detection of HCC. |
| Publish Date |
2017-03-24 09:18 |
| Citation |
Shaker MK, Abdel Fattah HI, Sabbour GS, Montasser IF, Abdelhakam SM, El Hadidy E, Yousry R, El Dorry AK. Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients. World J Hepatol 2017; 9(9): 469-476 |
| URL |
http://www.wjgnet.com/1948-5182/full/v9/i9/469.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v9.i9.469 |
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